2010
Telemonitoring in Patients with Heart Failure
Chaudhry SI, Mattera JA, Curtis JP, Spertus JA, Herrin J, Lin Z, Phillips CO, Hodshon BV, Cooper LS, Krumholz HM. Telemonitoring in Patients with Heart Failure. New England Journal Of Medicine 2010, 363: 2301-2309. PMID: 21080835, PMCID: PMC3237394, DOI: 10.1056/nejmoa1010029.Peer-Reviewed Original ResearchConceptsPrimary end pointUsual care groupSecondary end pointsHeart failureEnd pointHeart failure outcomesNumber of hospitalizationsTelephone-based interactive voice response systemUsual careAdverse eventsPatient's clinicianMedian ageCare groupLarge trialsInteractive voice response systemPatientsSmall studyVoice response systemNumber of daysHospitalizationReadmissionTelemonitoringSignificant differencesCliniciansDeathVariation in Recovery
Lichtman JH, Lorenze NP, D'Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in Recovery. Circulation Cardiovascular Quality And Outcomes 2010, 3: 684-693. PMID: 21081748, PMCID: PMC3064946, DOI: 10.1161/circoutcomes.109.928713.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI patientsAMI patientsYoung womenHeart diseaseSex differencesExcess mortality riskIschemic heart diseaseRisk stratification modelPsychosocial risk factorsYears of ageQuality of careComparison cohortPrognostic factorsPrognostic importanceAMI populationMyocardial infarctionRisk factorsObservational studyMortality riskHigh riskAMI eventsPatientsAge accountWomen
2008
An Administrative Claims Measure Suitable for Profiling Hospital Performance on the Basis of 30-Day All-Cause Readmission Rates Among Patients With Heart Failure
Keenan PS, Normand SL, Lin Z, Drye EE, Bhat KR, Ross JS, Schuur JD, Stauffer BD, Bernheim SM, Epstein AJ, Wang Y, Herrin J, Chen J, Federer JJ, Mattera JA, Wang Y, Krumholz HM. An Administrative Claims Measure Suitable for Profiling Hospital Performance on the Basis of 30-Day All-Cause Readmission Rates Among Patients With Heart Failure. Circulation Cardiovascular Quality And Outcomes 2008, 1: 29-37. PMID: 20031785, DOI: 10.1161/circoutcomes.108.802686.Peer-Reviewed Original ResearchConceptsRisk-standardized readmission ratesCause readmission rateReadmission ratesHeart failureHospital-level readmission ratesAdjusted readmission ratesAdministrative Claims MeasureUnadjusted readmission ratesHeart failure patientsHospital risk-standardized readmission ratesMedical record dataProfiling Hospital PerformanceHierarchical logistic regression modelsUse of MedicareMedical record modelNational Quality ForumLogistic regression modelsCause readmissionClaims-based modelsHospital dischargeFailure patientsC-statisticPreventable eventsPatientsQuality Forum
2007
Randomized Trial of Telemonitoring to Improve Heart Failure Outcomes (Tele-HF): Study Design
Chaudhry SI, Barton B, Mattera J, Spertus J, Krumholz HM. Randomized Trial of Telemonitoring to Improve Heart Failure Outcomes (Tele-HF): Study Design. Journal Of Cardiac Failure 2007, 13: 709-714. PMID: 17996818, PMCID: PMC2702538, DOI: 10.1016/j.cardfail.2007.06.720.Peer-Reviewed Case Reports and Technical NotesConceptsHeart failure outcomesHeart failureClinical statusFailure outcomesDecompensated heart failureHeart failure decompensationCare of patientsPrimary care practicesSelf-reported weightUsual careHospital readmissionDaily symptomsRandomized trialsGeneral cardiologyPatient participationHealth behaviorsCare practicesPatientsFrequent monitoringFavorable effectInterventionOutcomesSymptomsTrialsCareTelemonitoring for Patients With Chronic Heart Failure: A Systematic Review
Chaudhry SI, Phillips CO, Stewart SS, Riegel B, Mattera JA, Jerant AF, Krumholz HM. Telemonitoring for Patients With Chronic Heart Failure: A Systematic Review. Journal Of Cardiac Failure 2007, 13: 56-62. PMID: 17339004, PMCID: PMC1910700, DOI: 10.1016/j.cardfail.2006.09.001.BooksConceptsHeart failure patientsFailure patientsHeart failureHigh-risk heart failure patientsHigh-risk Hispanic populationMonitoring of signsChronic heart failureHeart failure hospitalizationLow-risk patientsDisease managementHigh-quality careFailure hospitalizationNegative studiesSymptom monitoringPatientsHealth statusMEDLINE databaseSystematic reviewQuality carePhysiologic monitoringIntervention typeEvidence baseSimilar effectivenessIntervention costsHispanic population
2006
Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley EH, Herrin J, Wang Y, Barton BA, Webster TR, Mattera JA, Roumanis SA, Curtis JP, Nallamothu BK, Magid DJ, McNamara RL, Parkosewich J, Loeb JM, Krumholz HM. Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction. New England Journal Of Medicine 2006, 355: 2308-2320. PMID: 17101617, DOI: 10.1056/nejmsa063117.Peer-Reviewed Original ResearchConceptsST-segment elevationBalloon timeCatheterization laboratoryMyocardial infarctionFaster doorEmergency departmentPrimary percutaneous coronary interventionHospital strategiesIntracoronary balloon inflationPercutaneous coronary interventionAcute myocardial infarctionMinority of hospitalsEmergency medicine physiciansReperfusion treatmentCoronary interventionBalloon inflationMedicine physiciansMultivariate analysisHospitalInfarctionPatientsMedicaid ServicesSignificant reductionReal-time data feedbackData feedback
2005
A Randomized Outpatient Trial of a Decision-Support Information Technology Tool
Apkon M, Mattera JA, Lin Z, Herrin J, Bradley EH, Carbone M, Holmboe ES, Gross CP, Selter JG, Rich AS, Krumholz HM. A Randomized Outpatient Trial of a Decision-Support Information Technology Tool. JAMA Internal Medicine 2005, 165: 2388-2394. PMID: 16287768, DOI: 10.1001/archinte.165.20.2388.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAttitude of Health PersonnelCost-Benefit AnalysisDecision Support Systems, ClinicalFemaleFloridaHealth ResourcesHospitals, MilitaryHumansKentuckyMaleMass ScreeningMultivariate AnalysisOutcome and Process Assessment, Health CarePatient SatisfactionPreventive MedicineQuality of Health CareConceptsProvider satisfactionAmbulatory clinic visitsUsual care patientsDays of enrollmentQuality process measuresQuality of careProportion of opportunitiesUsual careClinic visitsOutpatient trialSecondary outcomesPrimary outcomeAcute carePatient satisfactionIntervention groupHealth care opportunitiesPatientsClinical decisionCare opportunitiesPharmacy resourcesPreventive measuresProcess measuresCareMedical resourcesModest improvementKnowledge of blood pressure levels and targets in patients with coronary artery disease in the USA
Cheng S, Lichtman JH, Amatruda JM, Smith GL, Mattera JA, Roumanis SA, Krumholz HM. Knowledge of blood pressure levels and targets in patients with coronary artery disease in the USA. Journal Of Human Hypertension 2005, 19: 769-774. PMID: 16049521, DOI: 10.1038/sj.jhh.1001895.Peer-Reviewed Original ResearchConceptsBlood pressure levelsCoronary artery diseaseDiastolic blood pressure levelsArtery diseaseImportant modifiable risk factorTarget blood pressure levelsBlood pressure targetsHistory of hypertensionLow-risk patientsModifiable risk factorsCertain patient subgroupsHigh-risk groupBlood pressure knowledgePressure levelsClinical characteristicsPressure targetsRisk patientsPatient subgroupsPatient awarenessRisk factorsRisk groupsCardiac diseasePatientsDiseaseHypertensionKnowledge of Cholesterol Levels and Targets in Patients With Coronary Artery Disease
Cheng S, Lichtman JH, Amatruda JM, Smith GL, Mattera JA, Roumanis SA, Krumholz HM. Knowledge of Cholesterol Levels and Targets in Patients With Coronary Artery Disease. Preventive Cardiology 2005, 8: 11-17. PMID: 15722689, DOI: 10.1111/j.1520-037x.2005.3939.x.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseHigh-density lipoproteinLow-density lipoproteinCholesterol targetsArtery diseaseCholesterol levelsMultiple cardiac risk factorsCardiac risk factorsTotal cholesterol levelsTotal cholesterol valuesRisk factorsCardiovascular diseaseCholesterol valuesPrevious historyPatientsLipoproteinDiseaseCollege educationWomenNonwhitesEducation effortsNational targetsTargetCholesterol
2004
Quality of life after aortic valve replacement with tissue and mechanical implants
Sedrakyan A, Hebert P, Vaccarino V, Paltiel AD, Elefteriades JA, Mattera J, Lin Z, Roumanis SA, Krumholz HM. Quality of life after aortic valve replacement with tissue and mechanical implants. Journal Of Thoracic And Cardiovascular Surgery 2004, 128: 266-272. PMID: 15282464, DOI: 10.1016/j.jtcvs.2003.12.014.Peer-Reviewed Original ResearchConceptsAortic valve replacementQuality of lifeMechanical valve implantsMechanical valve recipientsValve replacementValve recipientsLife scoresValve implantsTissue valvesMechanical valvesMedical Outcomes Trust Short FormPopulation normsYale-New Haven HospitalMechanical valve replacementRate of complicationsUS population normsTissue valve replacementPrognostic factorsRole limitationsOnly significant differenceHealth SurveyAnalysis of covarianceBaseline qualityMean qualityPatientsClinical trial of an educational intervention to achieve recommended cholesterol levels in patients with coronary artery disease
Lichtman JH, Amatruda J, Yaari S, Cheng S, Smith GL, Mattera JA, Roumanis SA, Wang Y, Radford MJ, Krumholz HM. Clinical trial of an educational intervention to achieve recommended cholesterol levels in patients with coronary artery disease. American Heart Journal 2004, 147: 522-528. PMID: 14999204, DOI: 10.1016/j.ahj.2003.06.003.Peer-Reviewed Original ResearchConceptsLDL cholesterol target levelsCholesterol target levelsProportion of patientsCoronary artery diseaseUsual care groupArtery diseaseLevels 1 yearCholesterol managementCare groupEducational interventionPatient knowledgeLow-density lipoprotein cholesterol (LDL-C) target levelsTarget levelCholesterol knowledgeUsual careClinical characteristicsSecondary outcomesPrimary outcomeCholesterol levelsClinical trialsIntervention groupPatientsHospitalizationDiseaseIntervention
2003
Age does not limit quality of life improvement in cardiac valve surgery
Sedrakyan A, Vaccarino V, Paltiel AD, Elefteriades JA, Mattera JA, Roumanis SA, Lin Z, Krumholz HM. Age does not limit quality of life improvement in cardiac valve surgery. Journal Of The American College Of Cardiology 2003, 42: 1208-1214. PMID: 14522482, DOI: 10.1016/s0735-1097(03)00949-5.Peer-Reviewed Original ResearchConceptsMental component summaryQuality of lifeCardiac valve surgeryPhysical component summaryValve surgeryAssociation of ageValve proceduresComponent summarySF-36PCS scoresMedical Outcomes Trust Short FormPatients' QOLMitral valve proceduresAortic valve proceduresOlder patientsAortic patientsMCS scoresMitral patientsQOL benefitsHealth SurveyPatientsSurgeryStatistical significanceAgeMultiple regression analysis
2002
Randomized trial of an education and support intervention to preventreadmission of patients with heart failure
Krumholz HM, Amatruda J, Smith GL, Mattera JA, Roumanis SA, Radford MJ, Crombie P, Vaccarino V. Randomized trial of an education and support intervention to preventreadmission of patients with heart failure. Journal Of The American College Of Cardiology 2002, 39: 83-89. PMID: 11755291, DOI: 10.1016/s0735-1097(01)01699-0.Peer-Reviewed Original ResearchConceptsHeart failureSupport interventionsIntervention groupControl groupHospital readmission costsOne-year readmissionRate of readmissionAdverse clinical outcomesCost of careDisease management programsReadmission costsClinical outcomesHospital costsReadmissionLower riskPatientsOne-yearDemographic characteristicsInterventionTrialsGroupFormal educationTotal numberMedical componentsFailure
2001
A Qualitative Study of Increasing β-Blocker Use After Myocardial Infarction: Why Do Some Hospitals Succeed?
Bradley EH, Holmboe ES, Mattera JA, Roumanis SA, Radford MJ, Krumholz HM. A Qualitative Study of Increasing β-Blocker Use After Myocardial Infarction: Why Do Some Hospitals Succeed? JAMA 2001, 285: 2604-2611. PMID: 11368734, DOI: 10.1001/jama.285.20.2604.Peer-Reviewed Original ResearchConceptsBeta-blocker useAcute myocardial infarctionMyocardial infarctionΒ-blocker useStrong physician leadershipImprovement effortsUS hospitalsQualitative studyHospitalPatientsHospital sizeImprovement initiativesInfarctionKey physiciansGreater improvementPhysician leadershipCareAdministrative supportUse ratesPerformance improvement effortsData feedbackParticipantsGeographic regionsCliniciansMortality
1991
Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest
Kayden D, Sigal S, Soufer R, Mattera J, Zaret B, Wackers F. Thallium-201 for assessment of myocardial viability: Quantitative comparison of 24-hour redistribution imaging with imaging after reinjection at rest. Journal Of The American College Of Cardiology 1991, 18: 1480-1486. PMID: 1939949, DOI: 10.1016/0735-1097(91)90678-3.Peer-Reviewed Original ResearchConceptsInjection of thalliumRedistribution imagesDefect reversibilityThallium-201 reinjectionThallium-201 defectsLate redistribution imagingPoor quality studiesDiagnostic informationClinical variablesRedistribution imagingThallium defectsThallium imagesMyocardial viabilityReversible defectsStress imagingThallium-201PatientsBetter diagnostic informationStress testingExercisePresent studyQuality studiesInjectionLate redistributionReinjection