2024
Impact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic
Obradovic A, Toubat O, Chen N, Siebert A, Jansen C, Christophers B, Leveille E, Noch E, Kwan J. Impact of COVID-19 pandemic on physician-scientist trainees to faculty one year into the pandemic. BMC Medical Education 2024, 24: 587. PMID: 38807106, PMCID: PMC11134762, DOI: 10.1186/s12909-024-05541-9.Peer-Reviewed Original ResearchConceptsPersonal healthLong-term effects of COVID-19Physician-scientist traineesPhysician-scientistsCross-sectional survey of medical studentsCOVID-19 pandemicSurvey of medical studentsClustering techniqueScientific pursuitsHealth of familiesMultivariate regression analysisEffects of COVID-19ConclusionsThis national surveyLevel of trainingTailored supportPhysician-scientist trainingResearch productivityMental healthFewer physiciansLonger-term impactMedical studentsImpaired productionCOVID-19Long-term effectsReport concerns
2021
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Advances 2021, 5: 1164-1177. PMID: 33635335, PMCID: PMC7908851, DOI: 10.1182/bloodadvances.2020003568.Peer-Reviewed Original ResearchConceptsCritical illnessHealth system databaseNeutrophil activationCOVID-19Neutrophil activation signatureSevere COVID-19Intensive care unitGranulocyte colony-stimulating factorHigh mortality rateColony-stimulating factorSystem databaseHepatocyte growth factorClinical decompensationNeutrophil countImmune hyperactivationCare unitEarly elevationLipocalin-2Interleukin-8Longitudinal cohortClinical dataMortality ratePatientsIllnessActivation signature