Mechanisms underlying age differences in dopaminergic drug sensitivity
Dwyer J, Buntrock L, Khalaj A, Martinez L, Leslie F. Mechanisms underlying age differences in dopaminergic drug sensitivity. The FASEB Journal 2009, 23: 745.3-745.3. DOI: 10.1096/fasebj.23.1_supplement.745.3.Peer-Reviewed Original ResearchNeural stress systemsCritical developmental periodAge differencesNeural circuitryAdolescenceDevelopmental periodBehavioral differencesBehavioral responsesStress systemDrug abuseIndirect dopamineStereotypic behaviorAdolescentsNeuropsychiatric disordersD2-like agonist quinpiroleImportant implicationsAdult male ratsImmediate early gene expressionAgonist quinpiroleReceptor changesAdulthoodMale ratsAbuseEarly gene expressionQuinpirole