Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue
Zhang J, Laiwalla F, Kim JA, Urabe H, Van Wagenen R, Song YK, Connors BW, Zhang F, Deisseroth K, Nurmikko AV. Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue. Journal Of Neural Engineering 2009, 6: 055007. PMID: 19721185, PMCID: PMC2921864, DOI: 10.1088/1741-2560/6/5/055007.Peer-Reviewed Original ResearchConceptsMillisecond temporal controlIntegrated deviceNeural activityOptical stimulationHybrid deviceArray deviceProspective clinical treatmentMouse brain slicesOptical waveguidesOptical deliveryGanglion cellsBrain slicesNeurological diseasesRecording capabilitiesMouse retinaBrain tissueClinical treatmentElectrophysiological meansStimulation siteRecording arrayLocal deliveryDevicesRetinal photoreceptorsNeuronal spiking activityStimulation