Featured Publications
High epileptiform discharge burden predicts delayed cerebral ischemia after subarachnoid hemorrhage
Kim JA, Zheng WL, Elmer J, Jing J, Zafar SF, Ghanta M, Moura V, Gilmore EJ, Hirsch LJ, Patel A, Rosenthal E, Westover MB. High epileptiform discharge burden predicts delayed cerebral ischemia after subarachnoid hemorrhage. Clinical Neurophysiology 2021, 141: 139-146. PMID: 33812771, PMCID: PMC8429508, DOI: 10.1016/j.clinph.2021.01.022.Peer-Reviewed Original ResearchConceptsED burdenSubarachnoid hemorrhageEpileptiform dischargesCerebral ischemiaSAH patientsHigh riskOnset of DCIMajor risk periodContinuous EEG recordingsDCI patientsDCI riskRetrospective analysisNovel biomarkersGroup-based trajectory analysisRisk periodPatientsDay 3.5DCIBurdenHemorrhageIschemiaRiskEEG recordingsBurden rateUseful parameter
2024
Prognostic Implications of Early Prediction in Posttraumatic Epilepsy
Chen Y, Cappucci S, Kim J. Prognostic Implications of Early Prediction in Posttraumatic Epilepsy. Seminars In Neurology 2024, 44: 333-341. PMID: 38621706, DOI: 10.1055/s-0044-1785502.Peer-Reviewed Original ResearchPosttraumatic epilepsyTraumatic brain injuryComplication of traumatic brain injuryRisk of posttraumatic epilepsyPosttraumatic epilepsy modelBrain injuryPrognostic implicationsPrognostic informationIncreased morbidityClinical trajectoryTreatment strategiesPatient's clinical trajectoryRisk factorsHigh riskQuantitative prognostic information
2022
Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest
Beekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest. Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.Peer-Reviewed Original ResearchConceptsCardiac arrestBrain injuryHypoxic-ischemic brain injuryAdverse neurological outcomesIschemic brain injurySingle-center studyBrain magnetic resonanceBrain injury severityBoard-certified neuroradiologistsLow-field MRIFLAIR signal intensityNeurological outcomeCA patientsIll patientsMRI findingsCA survivorsCenter studyMRI examinationsClinical careHigh riskInjury severityPatientsSignal intensityBedside monitoringMR imaging
2017
Epileptiform abnormalities predict delayed cerebral ischemia in subarachnoid hemorrhage
Kim JA, Rosenthal ES, Biswal S, Zafar S, Shenoy AV, O'Connor KL, Bechek SC, Moura J, Shafi MM, Patel AB, Cash SS, Westover MB. Epileptiform abnormalities predict delayed cerebral ischemia in subarachnoid hemorrhage. Clinical Neurophysiology 2017, 128: 1091-1099. PMID: 28258936, PMCID: PMC5476529, DOI: 10.1016/j.clinph.2017.01.016.Peer-Reviewed Original ResearchConceptsCerebral ischemiaSubarachnoid hemorrhageRisk of DCISecondary cerebral injuryRhythmic delta activityAbnormal neural activityNew potential targetsCerebral injuryEarly patientsEpileptiform abnormalitiesMedical recordsEpileptiform dischargesRetrospective analysisHigh riskDCI developmentDelta activityPatientsNovel markerIschemiaSurvival analysis methodsCumulative probabilityPotential targetNeural activityNew markersDCI