2024
Plateau depolarizations in spontaneously active neurons detected by calcium or voltage imaging
Milicevic K, Ivanova V, Lovic D, Platisa J, Andjus P, Antic S. Plateau depolarizations in spontaneously active neurons detected by calcium or voltage imaging. Scientific Reports 2024, 14: 22787. PMID: 39367010, PMCID: PMC11452489, DOI: 10.1038/s41598-024-70319-4.Peer-Reviewed Original ResearchConceptsCa2+ transientsAction potentialsSpontaneously active neuronsCalcium imaging studiesCa2+ recordingsNeuronal action potentialsDepolarizing envelopeOptical signalsDendritic Ca2AP firingPlateau depolarizationsPyramidal neuronsMembrane depolarizationPlateau potentialsImaging studiesActive neuronsNeuronal culturesPhoton signaturesImaging modalitiesUP statesIn vivo conditionsNeuronsHalf-widthCa2+Depolarization
2023
High-speed low-light in vivo two-photon voltage imaging of large neuronal populations
Platisa J, Ye X, Ahrens A, Liu C, Chen I, Davison I, Tian L, Pieribone V, Chen J. High-speed low-light in vivo two-photon voltage imaging of large neuronal populations. Nature Methods 2023, 20: 1095-1103. PMID: 36973547, PMCID: PMC10894646, DOI: 10.1038/s41592-023-01820-3.Peer-Reviewed Original ResearchConceptsNeuronal populationsLarge neuronal populationsNeural circuit functionTwo-photon voltage imagingAwake behaving miceCalcium imagingBehaving miceVoltage imagingCircuit functionNeuronsShot noise levelShot-noise limitImagingTwo-photon microscopeKilohertz frame ratesDeep-tissue imagingPopulationVoltage indicatorsField of viewMiceShot noise