2001
Hepatocellular Carcinoma and Dysplastic Nodules in Patients with Cirrhosis: Prospective Diagnosis with MR Imaging and Explantation Correlation
Krinsky G, Lee V, Theise N, Weinreb J, Rofsky N, Diflo T, Teperman L. Hepatocellular Carcinoma and Dysplastic Nodules in Patients with Cirrhosis: Prospective Diagnosis with MR Imaging and Explantation Correlation. Radiology 2001, 219: 445-54. PMID: 11323471, DOI: 10.1148/radiology.219.2.r01ma40445.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaDysplastic nodulesMR imagingHistory of HCCSpecificity of MRDetection of HCCMagnetic resonanceDiagnosis of tumorsHepatic arterialHepatic malignanciesPathologic resultsHepatic neoplasmsProspective diagnosisGradient-echo MR imagesMR image interpretationPatient basisLesion basisMR imagesPatientsSubsequent transplantationSpin-echo MR imagesLesions 1Overall sensitivityDynamic contrast-enhanced three-dimensional MR imaging of liver parenchyma: source images and angiographic reconstructions to define hepatic arterial anatomy.
Lavelle M, Lee V, Rofsky N, Krinsky G, Weinreb J. Dynamic contrast-enhanced three-dimensional MR imaging of liver parenchyma: source images and angiographic reconstructions to define hepatic arterial anatomy. Radiology 2001, 218: 389-94. PMID: 11161151, DOI: 10.1148/radiology.218.2.r01fe31389.Peer-Reviewed Original ResearchSiderotic Nodules in the Cirrhotic Liver at MR Imaging with Explant Correlation: No Increased Frequency of Dysplastic Nodules and Hepatocellular Carcinoma
Krinsky G, Lee V, Nguyen M, Rofsky N, Theise N, Morgan G, Teperman L, Weinreb J. Siderotic Nodules in the Cirrhotic Liver at MR Imaging with Explant Correlation: No Increased Frequency of Dysplastic Nodules and Hepatocellular Carcinoma. Radiology 2001, 218: 47-53. PMID: 11152778, DOI: 10.1148/radiology.218.1.r01ja4047.Peer-Reviewed Original Research
2000
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Schmiedl U, Brown J, Borrello J, Lee J, Semelka R, Mattrey R, Dachman A, Saini S, Harms S, Mitchell D, Anderson M, Halford H, Bennett W, Young S, Rifkin M, Gay S, Ballerini R, Sherwin P, Robison R. Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. Journal Of Magnetic Resonance Imaging 2000, 12: 689-701. PMID: 11050638, DOI: 10.1002/1522-2586(200011)12:5<689::aid-jmri5>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsUnenhanced magnetic resonance imagingMagnetic resonance imagingMangafodipir trisodium injectionFinal diagnosisMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsContrast-enhanced magnetic resonance imagingInjection of MnDPDPPatient's final diagnosisHepatic magnetic resonance imagingComputed tomography examinationEnhanced magnetic resonance imagingFocal liver diseaseAdditional diagnostic informationFocal liver lesionsLiver diseaseEarly imagingMRI evaluationHepatic massClinical trialsTomography examinationIntravenous administrationPatient managementRadiologic diagnosisSiderotic Nodules at MR Imaging: Regenerative or Dysplastic?
Krinsky G, Lee V, Nguyen M, Rofsky N, Theise N, Morgan G, Teperman L, Weinreb J. Siderotic Nodules at MR Imaging: Regenerative or Dysplastic? Journal Of Computer Assisted Tomography 2000, 24: 773-776. PMID: 11045701, DOI: 10.1097/00004728-200009000-00019.Peer-Reviewed Original ResearchConceptsSiderotic nodulesMR imagingOrthotopic liver transplantationMagnetic resonance imagingSiderotic regenerative nodulesCirrhotic patientsLiver transplantationHypointense nodulesPathologic correlationRegenerative nodulesPatientsResonance imagingPrussian blue iron stainIron stainGradient echo pulse sequenceNodulesImagingMacronodularTransplantationSafety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety)
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Semelka R, Brown J, Borrello J, Lee J, Mattrey R, Dachman A, Saini S, Harmon B, Fenstermacher M, Pelsang R, Harms S, Mitchell D, Halford H, Anderson M, Johnson C, Francis I, Bova J, Kenney P, Klippenstein D, Foster G, Turner D, Stillman A, Nelson R, Young S, Patt R, Rifkin M, Seltzer S, Gay S, Robison R, Sherwin P, Ballerini R. Safety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety). Journal Of Magnetic Resonance Imaging 2000, 12: 186-197. PMID: 10931579, DOI: 10.1002/1522-2586(200007)12:1<186::aid-jmri21>3.0.co;2-2.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAged, 80 and overCardiovascular DiseasesContrast MediaDiagnosis, DifferentialEdetic AcidFemaleHumansImage EnhancementInjections, IntravenousLiver CirrhosisLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedPainPregnancyPyridoxal PhosphateRisk AssessmentSensitivity and SpecificityVomitingConceptsMagnetic resonance imagingMangafodipir trisodium injectionAdverse eventsMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsUnenhanced magnetic resonance imagingInjection of MnDPDPInjection-associated discomfortSerious adverse eventsShort-term safetyHepatic magnetic resonance imagingComputed tomography examinationSignificant short-term riskShort-term riskFocal liver lesionsClinical trialsTomography examinationLaboratory valuesLiver lesionsResonance imagingVital signsPatientsMnDPDPInjection
1998
Dysplastic nodules in cirrhotic liver: arterial phase enhancement at CT and MR imaging--a case report.
Krinsky G, Theise N, Rofsky N, Mizrachi H, Tepperman L, Weinreb J. Dysplastic nodules in cirrhotic liver: arterial phase enhancement at CT and MR imaging--a case report. Radiology 1998, 209: 461-4. PMID: 9807574, DOI: 10.1148/radiology.209.2.9807574.Peer-Reviewed Original Research
1996
Dysplastic nodules and hepatocellular carcinoma: thin-section MR imaging of explanted cirrhotic livers with pathologic correlation.
Earls J, Theise N, Weinreb J, DeCorato D, Krinsky G, Rofsky N, Mizrachi H, Teperman L. Dysplastic nodules and hepatocellular carcinoma: thin-section MR imaging of explanted cirrhotic livers with pathologic correlation. Radiology 1996, 201: 207-14. PMID: 8816545, DOI: 10.1148/radiology.201.1.8816545.Peer-Reviewed Original Research