Manganese (II) N,N'-dipyridoxylethylenediamine-N,N'-diacetate 5,5'-bis(phosphate): clinical experience with a new contrast agent.
Rofsky N, Weinreb J. Manganese (II) N,N'-dipyridoxylethylenediamine-N,N'-diacetate 5,5'-bis(phosphate): clinical experience with a new contrast agent. Magnetic Resonance Quarterly 1992, 8: 156-68. PMID: 1390058.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingMn-DPDPN'-dipyridoxylethylenediamineClinical experienceNon-enhanced T1Significant adverse eventsEnhanced magnetic resonance imagingManganese NT2-weighted imagesAdverse eventsHepatocellular originClinical trialsContrast agentsHepatobiliary agentsResonance imagingLiver imagingFavorable resultsLesion detectionNew contrast agentsIssues of safetyImaging techniquesAgentsImagingOptimal methodNumerous strategiesHepatic MR imaging with Mn-DPDP: safety, image quality, and sensitivity.
Bernardino M, Young S, Lee J, Weinreb J. Hepatic MR imaging with Mn-DPDP: safety, image quality, and sensitivity. Radiology 1992, 183: 53-8. PMID: 1549694, DOI: 10.1148/radiology.183.1.1549694.Peer-Reviewed Original ResearchConceptsMn-DPDPMore lesionsAdditional lesionsT1-weighted imagesDose groupSerious side effectsMagnetic resonance imagingT2-weighted imagesFocal hepatic diseaseN'-dipyridoxylethylenediamineIntravenous bolusHepatic diseaseMultiinstitutional studyPatientsSide effectsLesionsResonance imagingHepatic MRManganese NImaging parametersContrast agentsImagingGroupInfusionBolus