2020
Diuretic Therapy for Patients With Heart Failure JACC State-of-the-Art Review
Felker GM, Ellison DH, Mullens W, Cox ZL, Testani JM. Diuretic Therapy for Patients With Heart Failure JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2020, 75: 1178-1195. PMID: 32164892, DOI: 10.1016/j.jacc.2019.12.059.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHeart failureDiuretic therapyElevated intracardiac filling pressuresRobust clinical trial evidenceFailure JACC StateIntracardiac filling pressuresUse of diureticsClinical trial evidenceCornerstone of treatmentConstellation of signsMajor clinical challengeExtracellular fluid volumeDiuretic pharmacokineticsDiuretic regimenDiuretic resistanceLoop diureticsPoor prognosisTrial evidenceOutpatient settingJACC StateFilling pressureClinical challengeDiureticsRenal physiologyTherapy
2014
Acute Kidney Injury in the Era of Ventricular Assist Devices
Brisco M, Testani J. Acute Kidney Injury in the Era of Ventricular Assist Devices. 2014, 111-124. DOI: 10.1007/978-1-4939-1273-5_9.ChaptersAcute kidney injuryVentricular assist deviceRenal functionKidney injuryRenal dysfunctionAssist deviceDurable mechanical circulatory supportAdvanced heart failureMajority of patientsMechanical circulatory supportRenal outcomesCardiac transplantationVAD implantationVAD placementHeart failureCirculatory supportPoor prognosisDestination therapyClinical significanceSignificant burdenPatientsGreater riskDysfunctionTherapyInjury
2011
Clinical Characteristics and Outcomes of Patients With Improvement in Renal Function During the Treatment of Decompensated Heart Failure
Testani JM, McCauley BD, Chen J, Coca SG, Cappola TP, Kimmel SE. Clinical Characteristics and Outcomes of Patients With Improvement in Renal Function During the Treatment of Decompensated Heart Failure. Journal Of Cardiac Failure 2011, 17: 993-1000. PMID: 22123361, PMCID: PMC3248245, DOI: 10.1016/j.cardfail.2011.08.009.Peer-Reviewed Original ResearchConceptsDecompensated heart failureRenal functionHeart failureRenal dysfunctionAcute decompensated heart failureVolume of diuresisOutcomes of patientsCongestive heart failureGlomerular filtration rateCardiorenal interactionsIRF patientsClinical characteristicsHemodynamic derangementsConsecutive patientsCardiac dysfunctionDischarge diagnosisPoor prognosisFiltration rateMortality riskEligibility criteriaPatientsGreater incidenceDysfunctionUniversity of PennsylvaniaIRF
2010
Characteristics of Patients With Improvement or Worsening in Renal Function During Treatment of Acute Decompensated Heart Failure
Testani JM, McCauley BD, Kimmel SE, Shannon RP. Characteristics of Patients With Improvement or Worsening in Renal Function During Treatment of Acute Decompensated Heart Failure. The American Journal Of Cardiology 2010, 106: 1763-1769. PMID: 21055713, PMCID: PMC2997119, DOI: 10.1016/j.amjcard.2010.07.050.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseCardiotonic AgentsCatheterization, Swan-GanzCreatinineDisease ProgressionFemaleFollow-Up StudiesGlomerular Filtration RateHeart FailureHumansInfusions, IntravenousMaleMiddle AgedPrognosisPulmonary Wedge PressureRecovery of FunctionRenal InsufficiencyRetrospective StudiesStroke VolumeVasodilator AgentsConceptsDecompensated heart failureRenal functionStable renal functionCardiac indexHeart failureVasodilator usePulmonary Artery Catheterization Effectiveness trialAcute decompensated heart failureSimilar hemodynamic parametersCharacteristics of patientsCongestive heart failureComparison of patientsAdvanced disease stateCardiorenal interactionsIntravenous inotropesCause mortalityWorse survivalHemodynamic variablesPoor prognosisCreatinine valuesEffectiveness trialHemodynamic parametersHemodynamic differencesPatientsDisease states