2024
A Patient With Oral Discomfort and Reduced Oral Aperture
Chen G, Roy S, Cohen J. A Patient With Oral Discomfort and Reduced Oral Aperture. JAMA 2024, 331: 1147-1148. PMID: 38436993, DOI: 10.1001/jama.2023.25945.Peer-Reviewed Original ResearchReduced oral apertureHistory of cigarette smokingNo history of cigarette smokingLower labial mucosaOral apertureChewing areca nutBuccal mucosaOral discomfortOral mucosaSubepithelial fibrosisLabial mucosaNo historyCigarette smokingChewing tobaccoMucosaAreca nutPatientsBiopsyPainFibrosisOrallyDiagnosisComorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program
Kamal K, Xiang D, Young K, Mostaghimi A, Barbieri J, Cohen J, Theodosakis N. Comorbid psychiatric disease significantly mediates increased rates of alcohol use disorder among patients with inflammatory and pigmentary skin disorders: a case–control study in the All of Us Research Program. Archives Of Dermatological Research 2024, 316: 79. PMID: 38252292, DOI: 10.1007/s00403-023-02803-2.Peer-Reviewed Original ResearchConceptsAlcohol use disorderComorbid psychiatric diseaseUse disorderPsychiatric diseasesRates of alcohol use disordersOdds of alcohol use disordersContribution of depressionPhysical health effectsComorbid depressionMediation analysisAnxietyDepressionDisordersDermatological diseasesCase-control studyPigmentary skin disorderMultivariate logistic regressionHidradenitis suppurativaAtopic dermatitisSkin disordersPigmentary disordersCase-control modelIncreased oddsPatientsUs Research Program
2023
Depression in patients with Raynaud’s phenomenon: A case-control study in the National Institutes of Health's A ll of Us Research Program
Chen G, Shaw K, Xu S, Hashemi K, Castillo R, Vleugels R, Cohen J. Depression in patients with Raynaud’s phenomenon: A case-control study in the National Institutes of Health's A ll of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 90: 857-859. PMID: 38128831, DOI: 10.1016/j.jaad.2023.12.015.Peer-Reviewed Original ResearchBarriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US
Nock M, Kamal K, Zampella J, Roberson M, Cohen J, Barbieri J. Barriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US. JAMA Dermatology 2023, 159: 1323-1331. PMID: 37755822, PMCID: PMC10535014, DOI: 10.1001/jamadermatol.2023.3328.Peer-Reviewed Original ResearchConceptsChronic inflammatory skin diseaseInflammatory skin diseaseHealth care practitionersCross-sectional studySGM patientsPrevalence of barriersCare practitionersGender minority patientsSkin diseasesMinority patientsMAIN OUTCOMEHealth careMultivariable logistic regressionHealth care accessMental health careSpecialist careCare accessPatientsUs Research ProgramLogistic regressionCarePrevalenceDiseaseNational InstituteGender minority individualsObstructive sleep apnea among patients with psoriasis: A case-control study in the All of Us Research Program
Shaw V, Tobias L, Cohen J. Obstructive sleep apnea among patients with psoriasis: A case-control study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 90: 666-668. PMID: 38008412, DOI: 10.1016/j.jaad.2023.11.031.Peer-Reviewed Original ResearchRacial and Ethnic Differences Among Adult Patients Hospitalized for Skin and Soft Tissue Infection: A Cross-Sectional Analysis of 2012-2017 New York State Data.
Sedghi T, Cohen J, Feng H. Racial and Ethnic Differences Among Adult Patients Hospitalized for Skin and Soft Tissue Infection: A Cross-Sectional Analysis of 2012-2017 New York State Data. The Journal Of Clinical And Aesthetic Dermatology 2023, 16: 19-21. PMID: 38076657, PMCID: PMC10703506.Peer-Reviewed Original ResearchSoft tissue infectionsEthnic differencesStructural vulnerabilityHealthcare accessTissue infectionsAdult patientsNew York StateEthnic disparitiesDisparitiesEthnic minority patientsCost of hospitalizationLength of staySeverity of illnessIncreased healthcare costsClinical outcomesCross-sectional analysisWhite patientsPatientsInvestigate such differencesNewMachine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis
Murphy M, Hwang E, Singh K, Lee T, Cohen J, Damsky W. Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis. British Journal Of Dermatology 2023, 190: 132-134. PMID: 37818837, DOI: 10.1093/bjd/ljad389.Peer-Reviewed Original Research44140 Obsessive-Compulsive Disorder Among Patients with Atopic Dermatitis: A Case-Control Study in the All of Us Research Program
Chen G, Fan R, Leasure A, Damsky W, Cohen J. 44140 Obsessive-Compulsive Disorder Among Patients with Atopic Dermatitis: A Case-Control Study in the All of Us Research Program. Journal Of The American Academy Of Dermatology 2023, 89: ab69. DOI: 10.1016/j.jaad.2023.07.279.Peer-Reviewed Original ResearchIncreased risk of depression in patients with discoid lupus erythematosus: a nested, case–control study in the All of Us Research Program
Chen G, Shaw K, Sanchez-Melendez S, Vleugels R, Cohen J. Increased risk of depression in patients with discoid lupus erythematosus: a nested, case–control study in the All of Us Research Program. British Journal Of Dermatology 2023, 189: 628-629. PMID: 37461222, DOI: 10.1093/bjd/ljad239.Peer-Reviewed Original ResearchConceptsDiscoid lupus erythematosusCase-control studyRisk of depressionLupus erythematosusMajor depressive disorderHealth Research programmeDepressive disorderUs Research ProgramPatientsUS databaseLarge-scale studiesNational InstituteErythematosusRiskHeterogeneous populationDepressionFirst large-scale studyDemographic groupsImmune checkpoint inhibitor-induced bullous pemphigoid is characterized by interleukin (IL)-4 and IL-13 expression and responds to dupilumab treatment
Shipman W, Singh K, Cohen J, Leventhal J, Damsky W, Tomayko M. Immune checkpoint inhibitor-induced bullous pemphigoid is characterized by interleukin (IL)-4 and IL-13 expression and responds to dupilumab treatment. British Journal Of Dermatology 2023, 189: 339-341. PMID: 37140007, PMCID: PMC10947518, DOI: 10.1093/bjd/ljad149.Peer-Reviewed Original ResearchConceptsIL-13 expressionBullous pemphigoidImmune-related adverse eventsComplete disease clearancePromising new therapyNovel therapeutic approachesDisease clearanceAdverse eventsTumor immunityTherapeutic approachesNew therapiesConventional treatmentPemphigoidInterleukinTreatmentPatientsExpressionTherapyImmunityClearanceAutoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program
Murphy M, Edemobi P, Leasure A, Gulati M, Miller E, Damsky W, Cohen J. Autoimmune comorbidities associated with sarcoidosis: a case-control study in the All of Us research program. Rheumatology Advances In Practice 2023, 7: rkad030. PMID: 38606002, PMCID: PMC11007907, DOI: 10.1093/rap/rkad030.Peer-Reviewed Original ResearchCase-control studyAutoimmune diseasesSarcoidosis patientsMultivariable analysisOdds ratioSarcoidosis casesUs Research ProgramDiverse cohortConcomitant autoimmune diseasesRace-matched controlsMultiple autoimmune diseasesAutoimmune comorbiditiesSarcoidosisPatientsLogistic regressionDiseaseSmall sample sizeCareful screeningCohortAssociationSample sizeComposite variablePrior studiesComorbiditiesStudyAssociation of atopic dermatitis with schizophrenia and schizoaffective disorder: A case-control study in the All of Us Research Program
Fan R, Chen G, Leasure A, Johnson M, Damsky W, Cohen J. Association of atopic dermatitis with schizophrenia and schizoaffective disorder: A case-control study in the All of Us Research Program. 2023 DOI: 10.21203/rs.3.rs-2782847/v1.Peer-Reviewed Original ResearchAtopic dermatitisSchizoaffective disorderRace/ethnicityUs Research ProgramMental health comorbiditiesElectronic health record dataCase-control studyMajor depressive disorderHealth record dataDiagnosis of schizophreniaHealth comorbiditiesMultivariable analysisPathophysiologic mechanismsSmoking statusDepressive disorderAD casesSchizophreniaAnxiety disordersComparing RatesDisordersRecord dataNational InstituteFurther studiesPatientsDermatitisBaseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis
Singh K, Valido K, Swallow M, Okifo K, Wang A, Cohen J, Damsky W. Baseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis. Journal Of The American Academy Of Dermatology 2023, 88: 1094-1100. PMID: 36780951, DOI: 10.1016/j.jaad.2022.12.052.Peer-Reviewed Original ResearchConceptsEczematous dermatitisHistologic featuresTreatment selectionType 1Type 3 inflammationInflammatory skin diseaseCertain histologic featuresSitu hybridization correlatesClinical responseNonresponder groupCytokine profileCytokine stainingAtopic dermatitisCytokine RNAEczematous disordersSitu hybridizationDupilumabIL13 expressionSkin diseasesType 2PatientsDermatitisNonrespondersMolecular heterogeneityImproved response
2022
Patient perspectives on the lived experience of granuloma annulare
Clark A, Murphy M, King B, Cohen J, Rosenbach M, Barbieri J, Damsky W. Patient perspectives on the lived experience of granuloma annulare. British Journal Of Dermatology 2022, 188: 134-136. PMID: 36689498, DOI: 10.1093/bjd/ljac004.Peer-Reviewed Original ResearchRacial and ethnic differences in barriers to care among US adults with chronic inflammatory skin diseases: A cross-sectional study of the All of Us Research Program
Nock MR, Barbieri JS, Krueger LD, Cohen JM. Racial and ethnic differences in barriers to care among US adults with chronic inflammatory skin diseases: A cross-sectional study of the All of Us Research Program. Journal Of The American Academy Of Dermatology 2022, 88: 568-576. PMID: 36244557, DOI: 10.1016/j.jaad.2022.09.054.Peer-Reviewed Original ResearchConceptsChronic inflammatory skin diseaseInflammatory skin diseaseCross-sectional studyHispanic patientsUS adultsSkin diseasesUs Research ProgramEthnic differencesEthnic minority patientsHealth care workforce diversityWhite patientsAdult careMinority patientsMultivariable regressionPatientsDermatologic careCareDiseaseRepresentative sampleAdultsEthnic groupsStructural barriersEthnicityRural areasPrevalenceDepression and Anxiety in Patients With Lichen Sclerosus
Fan R, Leasure AC, Maisha FI, Little AJ, Cohen JM. Depression and Anxiety in Patients With Lichen Sclerosus. JAMA Dermatology 2022, 158: 953-954. PMID: 35704313, PMCID: PMC9201736, DOI: 10.1001/jamadermatol.2022.1964.Peer-Reviewed Original ResearchHidradenitis suppurativa and the risk of myocardial infarction, cerebrovascular accident, and peripheral vascular disease: a population-based study
Kridin K, Valido K, Cohen J, Cohen A. Hidradenitis suppurativa and the risk of myocardial infarction, cerebrovascular accident, and peripheral vascular disease: a population-based study. Archives Of Dermatological Research 2022, 315: 429-435. PMID: 35871185, DOI: 10.1007/s00403-022-02369-5.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseaseClalit Health ServicesCerebrovascular accidentHidradenitis suppurativaMyocardial infarctionHazard ratioVascular diseasePopulation-based retrospective cohort studyRisk of CVAIncidence of MIEthnicity-matched control subjectsMultivariate Cox regression analysisRisk of MIRetrospective cohort studyCox regression analysisOverall incidence ratePopulation-based studyCause mortalityCohort studyControl subjectsPrognostic outcomesEpidemiological findingsIncidence ratePatientsHealth servicesVaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide.
Fan R, Cohen JM. Vaccination Recommendations for Psoriasis and Atopic Dermatitis Patients on Biologic Therapy: A Practical Guide. The Yale Journal Of Biology And Medicine 2022, 95: 249-255. PMID: 35782480, PMCID: PMC9235258.Peer-Reviewed Original ResearchConceptsAtopic dermatitis patientsBiologic therapyVaccination recommendationsDermatitis patientsTreatment of psoriasisNovel biologic therapiesIL-17IL-23Atopic dermatitisIL-12/23Vaccine administrationClinical dataHealthcare providersAvailable guidelinesPsoriasisTherapyUnique considerationsPatientsPractical guideVaccinationDermatitisTNFαInfectionDermatologistsAdministration
2021
Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program
Fan R, Leasure AC, Damsky W, Cohen JM. Association between atopic dermatitis and COVID-19 infection: A case-control study in the All of Us research program. JAAD International 2021, 6: 77-81. PMID: 34977817, PMCID: PMC8712258, DOI: 10.1016/j.jdin.2021.12.007.Peer-Reviewed Original ResearchCOVID-19 infectionCase-control studyMultivariable analysisAD patientsAtopic dermatitis patientsCOVID-19 outcomesCOVID-19COVID-19 diagnosisElectronic health recordsCommon comorbiditiesAtopic dermatitisDermatitis patientsAD severityCOVID-19 casesUS cohortRisk factorsClinical dataAD casesUs Research ProgramComorbiditiesDiverse cohortPatientsInfectionCohortHealth recordsTrends in office visits and treatment for urticaria in children in the United States, 1998‐2016
Ugwu N, Cheraghlou S, Antaya RJ, Feng H, Cohen JM. Trends in office visits and treatment for urticaria in children in the United States, 1998‐2016. Pediatric Dermatology 2021, 38: 1162-1168. PMID: 34339077, DOI: 10.1111/pde.14726.Peer-Reviewed Original ResearchConceptsPediatric populationH1-antihistaminesTopical corticosteroidsFemale patientsNational Ambulatory Medical Care SurveyMost visitsAmbulatory Medical Care SurveyNon-corticosteroid therapySlight male predominanceFemale pediatric patientsMale predominancePediatric patientsTreatment guidelinesWhite patientsOffice visitsOutpatient recordsCare SurveyTreatment trendsUrticariaCommon conditionPatientsCalendar year 1998Age 18PediatriciansAntihistamines