2024
Barriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research Program
Nock M, Barbieri J, Cohen J. Barriers to care and health-related quality of life among US adults with several common chronic inflammatory skin diseases: a cross-sectional analysis of the NIH All of Us Research Program. Archives Of Dermatological Research 2024, 316: 201. PMID: 38775812, DOI: 10.1007/s00403-024-02954-w.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeHealth-related qualityUS adultsQuality of lifeSocial determinants of healthDeterminants of healthUs Research ProgramCross-sectional analysisNational Institutes of HealthSocial determinantsPhysician careInstitutes of HealthImpact of barriersCost barriersHRQoLAdultsNational InstituteHealthChronic inflammatory skin diseaseBarriersAoURPCarePhysiciansLifeInflammatory skin disease
2023
Barriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US
Nock M, Kamal K, Zampella J, Roberson M, Cohen J, Barbieri J. Barriers to Care Among Sexual and Gender Minority Individuals With Chronic Inflammatory Skin Diseases in the US. JAMA Dermatology 2023, 159: 1323-1331. PMID: 37755822, PMCID: PMC10535014, DOI: 10.1001/jamadermatol.2023.3328.Peer-Reviewed Original ResearchConceptsChronic inflammatory skin diseaseInflammatory skin diseaseHealth care practitionersCross-sectional studySGM patientsPrevalence of barriersCare practitionersGender minority patientsSkin diseasesMinority patientsMAIN OUTCOMEHealth careMultivariable logistic regressionHealth care accessMental health careSpecialist careCare accessPatientsUs Research ProgramLogistic regressionCarePrevalenceDiseaseNational InstituteGender minority individualsAssessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology
Mortlock R, Ma E, Cohen J, Damsky W. Assessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology. Journal Of Investigative Dermatology 2023, 143: 1412-1422. PMID: 37341663, PMCID: PMC10830170, DOI: 10.1016/j.jid.2023.04.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAtopic dermatitisSkin diseasesInflammatory skin diseaseInflammatory skin conditionImmunologic biomarkersImmune biomarkersPersonalized medicineInflammatory dermatosesImmunologic approachesTherapy selectionSkin conditionsSingle-cell RNA sequencingMolecular profilingBiomarkersTissue stainingPsoriasisDermatitisDiseaseDermatologyRNA sequencingMedicineCurettageDermatosesTherapyPersonalized classificationBaseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis
Singh K, Valido K, Swallow M, Okifo K, Wang A, Cohen J, Damsky W. Baseline skin cytokine profiles determined by RNA in situ hybridization correlate with response to dupilumab in patients with eczematous dermatitis. Journal Of The American Academy Of Dermatology 2023, 88: 1094-1100. PMID: 36780951, DOI: 10.1016/j.jaad.2022.12.052.Peer-Reviewed Original ResearchConceptsEczematous dermatitisHistologic featuresTreatment selectionType 1Type 3 inflammationInflammatory skin diseaseCertain histologic featuresSitu hybridization correlatesClinical responseNonresponder groupCytokine profileCytokine stainingAtopic dermatitisCytokine RNAEczematous disordersSitu hybridizationDupilumabIL13 expressionSkin diseasesType 2PatientsDermatitisNonrespondersMolecular heterogeneityImproved response
2022
The association of anxiety with granuloma annulare: a case–control study of the National Institutes of Health ‘All of Us’ research programme
Belzer A, Leasure A, Damsky W, Cohen J. The association of anxiety with granuloma annulare: a case–control study of the National Institutes of Health ‘All of Us’ research programme. British Journal Of Dermatology 2022, 188: 558-560. PMID: 36715356, DOI: 10.1093/bjd/ljac114.Peer-Reviewed Original ResearchConceptsCase-control studyGranuloma annulareMental health conditionsInflammatory dermatosesHealth conditionsInflammatory skin diseaseImprovement of depressionAssociation of anxietyPost-traumatic stress disorderOpioid dependenceAutoimmune disordersProinflammatory cytokinesBody of evidenceDear EditorSkin diseasesSignificant associationDermatosesStress disorderNational InstituteAnnulareAssociationDisordersDepressionAnxietyDyslipidaemiaPatient perspectives on the lived experience of granuloma annulare
Clark A, Murphy M, King B, Cohen J, Rosenbach M, Barbieri J, Damsky W. Patient perspectives on the lived experience of granuloma annulare. British Journal Of Dermatology 2022, 188: 134-136. PMID: 36689498, DOI: 10.1093/bjd/ljac004.Peer-Reviewed Original ResearchRacial and ethnic differences in barriers to care among US adults with chronic inflammatory skin diseases: A cross-sectional study of the All of Us Research Program
Nock MR, Barbieri JS, Krueger LD, Cohen JM. Racial and ethnic differences in barriers to care among US adults with chronic inflammatory skin diseases: A cross-sectional study of the All of Us Research Program. Journal Of The American Academy Of Dermatology 2022, 88: 568-576. PMID: 36244557, DOI: 10.1016/j.jaad.2022.09.054.Peer-Reviewed Original ResearchConceptsChronic inflammatory skin diseaseInflammatory skin diseaseCross-sectional studyHispanic patientsUS adultsSkin diseasesUs Research ProgramEthnic differencesEthnic minority patientsHealth care workforce diversityWhite patientsAdult careMinority patientsMultivariable regressionPatientsDermatologic careCareDiseaseRepresentative sampleAdultsEthnic groupsStructural barriersEthnicityRural areasPrevalence
2021
Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis
Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.Peer-Reviewed Original ResearchAtopic dermatitisAtopic dermatitis casesInflammatory skin diseaseInflammatory skin disorderSubset of casesSitu hybridizationCytokine RNARoutine biopsyCytokine expressionPredominant cytokinePsoriasis casesCytokine targetsTreatment selectionDermatitis casesSkin disordersPsoriasis biomarkersSkin diseasesIndividual cytokinesIndividualized evaluationPsoriasisBiopsyBulk RNA sequencingCytokinesMolecular phenotypingPatients
2018
Psoriasis and suicidality: A review of the literature
Liang SE, Cohen JM, Ho RS. Psoriasis and suicidality: A review of the literature. Dermatologic Therapy 2018, 32: e12771. PMID: 30315629, DOI: 10.1111/dth.12771.Peer-Reviewed Original ResearchConceptsSuicidal ideationSystemic inflammatory skin diseaseEvidence-based clinical decisionsInflammatory skin diseasePsoriasis populationBiologic therapyPsoriasis patientsPsychiatric comorbidityPsoriasisSkin diseasesClinical decisionSuicide attemptsAvailable evidenceSuicidalityMultiple studiesPlausible molecular mechanismPresent reviewAvailable literatureMolecular mechanismsIdeationRiskAssociationReviewComorbiditiesPatients