1999
Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis
Russell K, Stern D, Polverini P, Bender J. Neuregulin activation of ErbB receptors in vascular endothelium leads to angiogenesis. American Journal Of Physiology 1999, 277: h2205-h2211. PMID: 10600838, DOI: 10.1152/ajpheart.1999.277.6.h2205.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedCorneaEndothelial Growth FactorsEndothelium, VascularErbB ReceptorsHumansLymphokinesMiceNeovascularization, PhysiologicNeuregulinsRatsReceptor, ErbB-2Receptor, ErbB-3Receptor, ErbB-4ThrombinUmbilical VeinsVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsHuman umbilical vein endothelial cellsVascular endotheliumErbB receptorsReceptor tyrosine phosphorylationStimulation of HUVECsRapid calcium fluxReceptor family membersEndothelial cell growth factorTransmembrane tyrosine kinase receptorVascular endothelial cell growth factorEndothelial cell signalingReceptor-ligand interactionsTyrosine kinase receptorsEpidermal growth factor receptorVascular endothelial growthCell growth factorUmbilical vein endothelial cellsCell signalingGrowth factor receptorTyrosine phosphorylationVivo angiogenic responseExpression patternsGrowth regulationVein endothelial cellsIntracellular signaling
1992
Early recognition of a discordant xenogeneic organ by human circulating lymphocytes.
Inverardi L, Samaja M, Motterlini R, Mangili F, Bender J, Pardi R. Early recognition of a discordant xenogeneic organ by human circulating lymphocytes. The Journal Of Immunology 1992, 149: 1416-23. PMID: 1386865, DOI: 10.4049/jimmunol.149.4.1416.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteCD3 ComplexCell AdhesionCytotoxicity, ImmunologicEndothelium, VascularHeart TransplantationHumansImmunity, CellularKiller Cells, NaturalLymphocyte Function-Associated Antigen-1Lymphocyte SubsetsMyocardiumRatsReceptors, Antigen, T-CellReceptors, FcReceptors, IgGTransplantation, HeterologousConceptsNK cellsXenogeneic organsCell-mediated immune mechanismsHuman lymphocytesAntibody-independent pathwayLymphocyte phenotypic analysisCell-mediated mechanismsHuman NK cellsNK cell adhesionPretreatment of lymphocytesAnti-CD18 antibodiesDiscordant xenograft rejectionHuman circulating lymphocytesEx vivo modelRat endothelial cellsCD3-CD16Vascular resistanceLymphocyte subsetsXenograft rejectionCirculating lymphocytesCoronary systemEarly recognitionImmune mechanismsT lymphocytesCell sequestrationCellular early immune recognition of xenogeneic vascular endothelium.
Inverardi L, Samaja M, Marelli F, Bender J, Pardi R. Cellular early immune recognition of xenogeneic vascular endothelium. Transplantation Proceedings 1992, 24: 459-61. PMID: 1566390.Peer-Reviewed Original Research
1989
EVIDENCE THAT CYTOTOXIC LYMPHOCYTES ALTER AND TRAVERSE ALLOGENEIC ENDOTHELIAL CELL MONOLAYERS
BENDER J, PARDI R, KOSEK J, ENGLEMAN E. EVIDENCE THAT CYTOTOXIC LYMPHOCYTES ALTER AND TRAVERSE ALLOGENEIC ENDOTHELIAL CELL MONOLAYERS. Transplantation 1989, 47: 1047-1052. PMID: 2660343, DOI: 10.1097/00007890-198906000-00026.Peer-Reviewed Original ResearchConceptsAllogeneic endothelial cellsEndothelial cellsClass II major histocompatibility complex antigensMajor histocompatibility complex antigensLymphocyte-EC adhesionHistocompatibility complex antigensEC monolayersSame morphologic changesAllogeneic lymphocytesLymphocyte subsetsLymphocyte subpopulationsAutologous combinationsEndothelial cell monolayersSuch lymphocytesSurface phenotypeComplex antigensIntact EC monolayerRecombinant cytokinesMorphologic changesLymphocytesCell monolayersEC barrierFunctional consequencesCurrent findingsCellular interactions