2000
Estrogen Stimulates Heat Shock Protein 90 Binding to Endothelial Nitric Oxide Synthase in Human Vascular Endothelial Cells EFFECTS ON CALCIUM SENSITIVITY AND NO RELEASE*
Russell K, Haynes M, Caulin-Glaser T, Rosneck J, Sessa W, Bender J. Estrogen Stimulates Heat Shock Protein 90 Binding to Endothelial Nitric Oxide Synthase in Human Vascular Endothelial Cells EFFECTS ON CALCIUM SENSITIVITY AND NO RELEASE*. Journal Of Biological Chemistry 2000, 275: 5026-5030. PMID: 10671543, DOI: 10.1074/jbc.275.7.5026.Peer-Reviewed Original ResearchConceptsEndothelial nitric oxide synthaseNitric oxide synthaseHuman umbilical vein endothelial cellsENOS activationOxide synthaseEstrogen receptor antagonist ICINO releaseEndothelium-dependent vasodilationReceptor-mediated modulationReceptor antagonist ICINitric oxide releaseUmbilical vein endothelial cellsVein endothelial cellsAntagonist ICIHeat shock protein 90CGMP productionShock protein 90Oxide releaseEndothelial cellsEndothelial cell effectsCalcium sensitivityCalcium dependenceCell effectsEstrogenProtein 90
1996
Tumor necrosis factor alpha-induced vascular leakage involves PECAM1 phosphorylation.
Ferrero E, Villa A, Ferrero M, Toninelli E, Bender J, Pardi R, Zocchi M. Tumor necrosis factor alpha-induced vascular leakage involves PECAM1 phosphorylation. Cancer Research 1996, 56: 3211-5. PMID: 8764109.Peer-Reviewed Original ResearchMeSH KeywordsAlkaloidsAntigens, Differentiation, MyelomonocyticBenzoquinonesCapillary PermeabilityCell Adhesion MoleculesCell CompartmentationCells, CulturedEndothelium, VascularEnzyme InhibitorsFluorescent Antibody Technique, IndirectGene ExpressionHumansLactams, MacrocyclicPhosphorylationPlatelet Endothelial Cell Adhesion Molecule-1Protein Kinase InhibitorsQuinonesRifabutinRNA, MessengerStaurosporineTumor Necrosis Factor-alphaUmbilical VeinsConceptsVascular leakageEndothelial cellsNecrosis factor alphaTyrosine kinase inhibitorsHuman umbilical vein endothelial cellsUmbilical vein endothelial cellsNatural tyrosine kinase inhibitorSerine-threonine kinaseVein endothelial cellsSurface redistributionFactor alphaVascular permeabilityVivo administrationKinase inhibitorsCytoskeletal associationMouse liverLavendustin AUse of inhibitorsPhosphorylationInhibitors