Tumor necrosis factor alpha-induced vascular leakage involves PECAM1 phosphorylation.
Ferrero E, Villa A, Ferrero M, Toninelli E, Bender J, Pardi R, Zocchi M. Tumor necrosis factor alpha-induced vascular leakage involves PECAM1 phosphorylation. Cancer Research 1996, 56: 3211-5. PMID: 8764109.Peer-Reviewed Original ResearchMeSH KeywordsAlkaloidsAntigens, Differentiation, MyelomonocyticBenzoquinonesCapillary PermeabilityCell Adhesion MoleculesCell CompartmentationCells, CulturedEndothelium, VascularEnzyme InhibitorsFluorescent Antibody Technique, IndirectGene ExpressionHumansLactams, MacrocyclicPhosphorylationPlatelet Endothelial Cell Adhesion Molecule-1Protein Kinase InhibitorsQuinonesRifabutinRNA, MessengerStaurosporineTumor Necrosis Factor-alphaUmbilical VeinsConceptsVascular leakageEndothelial cellsNecrosis factor alphaTyrosine kinase inhibitorsHuman umbilical vein endothelial cellsUmbilical vein endothelial cellsNatural tyrosine kinase inhibitorSerine-threonine kinaseVein endothelial cellsSurface redistributionFactor alphaVascular permeabilityVivo administrationKinase inhibitorsCytoskeletal associationMouse liverLavendustin AUse of inhibitorsPhosphorylationInhibitors