T-cell receptor-negative natural killer cells display antigen-specific cytotoxicity for microvascular endothelial cells.
Bender J, Pardi R, Engleman E. T-cell receptor-negative natural killer cells display antigen-specific cytotoxicity for microvascular endothelial cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 6949-6953. PMID: 2402485, PMCID: PMC54659, DOI: 10.1073/pnas.87.18.6949.Peer-Reviewed Original ResearchConceptsMicrovascular endothelial cellsEndothelial cellsNK cellsNatural killer cell targetsNatural killer cellsAllogeneic endothelial cellsAntigen-specific cytotoxicityNK cell linesCD3/T cell receptorLevel of adherenceEC linesHuman microvascular endothelial cellsT cell receptorOrgan allograftsGamma chain geneKiller cellsLymphoid cellsSpecific cytotoxicityCell targetsNegative cellsCell linesHuman erythroleukemia cellsSelective cytotoxicityTi moleculesCytotoxicity