Fresh Murine Red Blood Cells Abrogate the Enhanced Alloimmunogenicity of Stored Murine Red Blood Cells
Hendrickson J, Hod E, Spitalnik S, Zimring J. Fresh Murine Red Blood Cells Abrogate the Enhanced Alloimmunogenicity of Stored Murine Red Blood Cells. Blood 2010, 116: 663. DOI: 10.1182/blood.v116.21.663.663.Peer-Reviewed Original ResearchFresh red blood cellsStored red blood cellsMurine red blood cellsRed blood cellsOld red blood cellsBlood cellsMurine modelFlow cytometric crossmatchRandomized clinical studyRates of immunizationYoung red blood cellsAdditional control animalsCPDA-1Alloimmunization rateFVB controlsAlloantibody responsesAlloimmune responseC57BL/6 recipientsCytometric crossmatchPotential deleterious effectsImmunoregulatory propertiesWorse outcomesClinical dataClinical studiesAntigen expression