2004
Parasitological resistance of Plasmodium falciparum to antimalarial drugs: what physicians should keep in mind.
Tinto H, Ouédraogo J, Traoré M, Guiguemdé T. Parasitological resistance of Plasmodium falciparum to antimalarial drugs: what physicians should keep in mind. Cahiers De Santé 2004, 14: 69-73. PMID: 15454363.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntimalarialsDrug Resistance, MicrobialHumansImmune SystemMalaria, FalciparumPlasmodium falciparumConceptsMalaria case managementParasitological resistanceAntimalarial drugsCase managementDrug resistancePlasmodium falciparum drug resistanceSemi-immune subjectsNon-immune subjectsMalaria drug resistanceAttitudes of physiciansSelective drug pressurePublic health practiceTherapeutic decisionsDrug pressureHost immunityParasitological resultsHealth practicesClinical levelPlasmodium falciparumResistant strainsPhysiciansDrugsLower proportionVivoClassification system
2003
Relationship between the Pfcrt T76 and the Pfmdr-1 Y86 mutations in Plasmodium falciparum and in vitro/in vivo chloroquine resistance in Burkina Faso, West Africa
Tinto H, Ouédraogo J, Erhart A, Van Overmeir C, Dujardin J, Van Marck E, Guiguemdé T, D’Alessandro U. Relationship between the Pfcrt T76 and the Pfmdr-1 Y86 mutations in Plasmodium falciparum and in vitro/in vivo chloroquine resistance in Burkina Faso, West Africa. Infection Genetics And Evolution 2003, 3: 287-292. PMID: 14636690, DOI: 10.1016/j.meegid.2003.08.002.Peer-Reviewed Original ResearchConceptsPfcrt T76 mutationT76 mutationPfcrt T76CQ resistancePlasmodium falciparumVivo chloroquine resistancePre-treatment samplesPfcrt K76Uncomplicated malariaChloroquine resistanceStrong linkage disequilibriumGeometric mean valuesBurkina FasoSuch associationsChloroquinePrevious reportsFalciparumMutationsT76