2015
Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis
Poulos MG, Crowley MJP, Gutkin MC, Ramalingam P, Schachterle W, Thomas JL, Elemento O, Butler JM. Vascular Platform to Define Hematopoietic Stem Cell Factors and Enhance Regenerative Hematopoiesis. Stem Cell Reports 2015, 5: 881-894. PMID: 26441307, PMCID: PMC4649106, DOI: 10.1016/j.stemcr.2015.08.018.Peer-Reviewed Original ResearchConceptsBM endothelial cellsHematopoietic stem cellsBone marrowDevelopment of therapiesAdult bone marrowCytokine profileMyeloablative regimensMyeloablative irradiationStem cell factorRegenerative hematopoiesisPerivascular cellsCellular therapyEndothelial cellsDisease statesCytokine supplementationVascular platformCell factorVascular nicheTherapyPrevious reportsStem cells
2010
A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry
Hallani S, Boisselier B, Peglion F, Rousseau A, Colin C, Idbaih A, Marie Y, Mokhtari K, Thomas JL, Eichmann A, Delattre JY, Maniotis AJ, Sanson M. A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry. Brain 2010, 133: 973-982. PMID: 20375132, PMCID: PMC4861203, DOI: 10.1093/brain/awq044.Peer-Reviewed Original ResearchConceptsStem-like cellsGlioblastoma stem-like cellsVascular smooth muscle-like cellsSmooth muscle-like cellsAnti-angiogenic therapyMuscle-like cellsHuman glioblastoma tissuesTransient efficacyTreatment strategiesStem cell propertiesEndothelial proliferationVasculogenic mimicryTumor cellsHuman tumorsBlood vesselsGlioblastoma vasculatureGlioblastoma tissuesGlioblastoma cellsVascularizationCellsDe novoGene expressionNew alternative mechanismTherapyTumors