Perinuclear antineutrophilic cytoplasmic antibody-positive cutaneous polyarteritis nodosa associated with minocycline therapy for acne vulgaris
Schaffer J, Davidson D, McNiff J, Bolognia J. Perinuclear antineutrophilic cytoplasmic antibody-positive cutaneous polyarteritis nodosa associated with minocycline therapy for acne vulgaris. Journal Of The American Academy Of Dermatology 2001, 44: 198-206. PMID: 11174376, DOI: 10.1067/mjd.2001.112218.Peer-Reviewed Case Reports and Technical NotesConceptsLong-term minocycline therapyCutaneous polyarteritis nodosaAntineutrophil cytoplasmic antibodyPolyarteritis nodosaMinocycline therapyCytoplasmic antibodiesSubcutaneous nodulesAcne vulgarisPerinuclear antineutrophil cytoplasmic antibodyAntinuclear antibody panelDiscontinuation of minocyclineDrug-induced lupusUnusual side effectMedium-sized arteriesLong-term treatmentAutoimmune hepatitisOral antibioticsPrednisone therapyLivedo reticularisAutoimmune syndromeAutoimmune disordersCutaneous lesionsBiopsy specimensLower extremitiesHistologic examination