2020
Clinical factors associated with acute exacerbations of chronic rhinosinusitis
Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A, Schleimer RP, Peters AT. Clinical factors associated with acute exacerbations of chronic rhinosinusitis. Journal Of Allergy And Clinical Immunology 2020, 145: 1598-1605. PMID: 32004523, PMCID: PMC8177481, DOI: 10.1016/j.jaci.2020.01.023.Peer-Reviewed Original ResearchConceptsFrequent acute exacerbationsChronic rhinosinusitisAcute exacerbationAllergic rhinitisClinical factorsEosinophil countAutoimmune diseasesSignificant health care burdenSinus disease severityRetrospective cohort studySystemic corticosteroid useHealth care burdenHigh-risk phenotypeAntibiotic allergyExacerbation frequencyFrequent exacerbationsSinus symptomsCorticosteroid useCohort studyLower FEVNasal polyposisAntibody deficiencyImpaired qualityImmunologic diseasesOdds ratio
2019
Asthma in adults: Principles of treatment.
Kwah JH, Peters AT. Asthma in adults: Principles of treatment. Allergy & Asthma Proceedings 2019, 40: 396-402. PMID: 31690379, DOI: 10.2500/aap.2019.40.4256.Peer-Reviewed Original ResearchConceptsAllergen immunotherapyAllergic asthmaBetter long-term controlModerate allergic asthmaT2-high asthmaType 2 inflammationGastroesophageal reflux diseasePrevention of exacerbationsAllergen-specific immunotherapyEmergency department visitsPhysical examination findingsExpiratory flow rateGoal of treatmentPrinciples of treatmentReduction of symptomsSeverity of symptomsNormal activity levelsLong-term controlReflux diseaseSevere asthmaAllergic rhinitisAsthma symptomsBiologic therapyPulmonary functionSelect patientsAsthma and allergies in pregnancy.
Kwah JH, Stevens WW. Asthma and allergies in pregnancy. Allergy & Asthma Proceedings 2019, 40: 414-417. PMID: 31690383, PMCID: PMC8242985, DOI: 10.2500/aap.2019.40.4260.Peer-Reviewed Original ResearchConceptsMedical therapyStandard medical therapyNormal physiologic changesCommon respiratory diseasesCourse of asthmaBenefits of medicationsEvaluation of symptomsUncontrolled asthmaAllergic rhinitisPulmonary functionVasomotor rhinitisComorbid conditionsPregnant womenPhysiologic changesPatient educationRespiratory diseaseAsthmaGeneral populationMost womenPregnancyAppropriate managementEnvironmental exposuresRhinitisTherapyRisk