2011
Induction of Persistent Depressive-Like Behavior by Corticosterone
Gourley S, Taylor J. Induction of Persistent Depressive-Like Behavior by Corticosterone. Neuromethods 2011, 63: 251-265. DOI: 10.1007/978-1-61779-313-4_16.Peer-Reviewed Original ResearchChronic CORT exposureDepressive-like behaviorCORT exposureChronic depressive-like stateChronic mild stress modelStress-related mood disordersChronic antidepressant treatmentSerum CORT levelsNeurobiology of depressionDepressive-like stateChronic oral exposureCharacteristics of depressionAntidepressant efficacyAntidepressant treatmentAdrenal hormonesOral exposureMood disordersFeelings of anhedoniaLocomotor activityNaïve rodentsCORT levelsCorticosteroneDepressionBehavioral consequencesExposure
2009
Recapitulation and Reversal of a Persistent Depression‐like Syndrome in Rodents
Gourley SL, Taylor JR. Recapitulation and Reversal of a Persistent Depression‐like Syndrome in Rodents. Current Protocols In Neuroscience 2009, 49: 9.32.1-9.32.11. PMID: 19802817, PMCID: PMC2774936, DOI: 10.1002/0471142301.ns0932s49.Peer-Reviewed Original ResearchConceptsCORT exposureChronic mild stress modelChronic antidepressant treatmentChronic CORT exposureHelplessness-like behaviorDepressive-like stateNeurobiology of depressionDepression-like syndromeChronic oral exposureAntidepressant efficacyAntidepressant treatmentAdrenal hormonesOral exposureNucleus accumbensMouse modelFeelings of anhedoniaNaïve rodentsMultiple biological functionsMolecular targetsCAMP response elementDepressionFactor activityCorticosteroneExposure periodExposure