2017
Mecamylamine treatment for alcohol dependence: a randomized controlled trial
Petrakis IL, Ralevski E, Gueorguieva R, O'Malley SS, Arias A, Sevarino KA, Jane JS, O'Brien E, Krystal JH. Mecamylamine treatment for alcohol dependence: a randomized controlled trial. Addiction 2017, 113: 6-14. PMID: 28710873, PMCID: PMC5725262, DOI: 10.1111/add.13943.Peer-Reviewed Original ResearchConceptsHeavy drinking daysDrinking daysAlcohol use disorderUse disordersAlcohol consumptionAlcohol dependenceDouble-blind clinical trialNicotinic acetylcholine receptor antagonistWeeks of treatmentAcetylcholine receptor antagonistCurrent alcohol dependenceSignificant differencesTreatment-seeking smokersMecamylamine treatmentPlacebo groupMonth 3Primary outcomeSmoking statusNicotine withdrawalReceptor antagonistNovel pharmacotherapiesClinical trialsManagement therapyMecamylamineTreatment groups
2015
Prazosin for Veterans with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence: A Clinical Trial
Petrakis IL, Desai N, Gueorguieva R, Arias A, O'Brien E, Jane JS, Sevarino K, Southwick S, Ralevski E. Prazosin for Veterans with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence: A Clinical Trial. Alcohol Clinical And Experimental Research 2015, 40: 178-186. PMID: 26683790, DOI: 10.1111/acer.12926.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderUse of prazosinSymptoms of PTSDComorbid alcohol dependenceAlcohol dependenceClinical trialsComorbid conditionsSleep disturbancesNoradrenergic dysregulationAlcohol consumptionStress disorderTreatment of PTSDPTSD symptomsHigh clinical importanceMedication groupPharmacologic optionsPromising medicationMedication effectsMAIN OUTCOMEEffective treatmentPrazosinComorbid disordersClinical importancePsychosocial functionClinical issues
2013
Characteristics and drinking patterns of veterans with alcohol dependence with and without post-traumatic stress disorder
Fuehrlein B, Ralevski E, O'Brien E, Jane JS, Arias AJ, Petrakis IL. Characteristics and drinking patterns of veterans with alcohol dependence with and without post-traumatic stress disorder. Addictive Behaviors 2013, 39: 374-378. PMID: 24090619, DOI: 10.1016/j.addbeh.2013.08.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenergic alpha-AntagonistsAdultAgedAlcohol DrinkingAlcoholismComorbidityConnecticutDiagnosis, Dual (Psychiatry)FemaleHumansMaleMassachusettsMecamylamineMental DisordersMiddle AgedNicotinic AntagonistsPlacebosPrazosinPsychotropic DrugsSeverity of Illness IndexStress Disorders, Post-TraumaticSubstance-Related DisordersTreatment OutcomeVeteransYoung AdultConceptsPost-traumatic stress disorderCo-occurring illnessesAlcohol dependenceStress disorderCo-occurring alcohol dependenceDetailed drinking historiesDifferent treatment studiesMajor depressive episodeClinical treatment settingsHeavy drinking daysAlcohol use disorderPre-treatment characteristicsBaseline characteristicsDepressive episodePsychiatric symptomsUse disordersDrinking daysDomains of psychopathologyTreatment settingsDrinking historyTreatment studiesPsychopathological domainsPTSD groupPTSD symptomsMore days
2007
Gender Bias in Diagnostic Criteria for Personality Disorders: An Item Response Theory Analysis
Jane J, Oltmanns T, South S, Turkheimer E. Gender Bias in Diagnostic Criteria for Personality Disorders: An Item Response Theory Analysis. Journal Of Psychopathology And Clinical Science 2007, 116: 166-175. PMID: 17324027, PMCID: PMC4372614, DOI: 10.1037/0021-843x.116.1.166.Peer-Reviewed Original Research
2002
Gender role and personality disorders.
Klonsky E, Jane J, Turkheimer E, Oltmanns T. Gender role and personality disorders. Journal Of Personality Disorders 2002, 16: 464-76. PMID: 12489312, PMCID: PMC4364134, DOI: 10.1521/pedi.16.5.464.22121.Peer-Reviewed Original Research
1998
Glucose Effects on Cognition in Adults With Down's Syndrome
Manning C, Honn V, Stone W, Jane J, Gold P. Glucose Effects on Cognition in Adults With Down's Syndrome. Neuropsychology 1998, 12: 479-484. PMID: 9674002, DOI: 10.1037/0894-4105.12.3.479.Peer-Reviewed Original ResearchConceptsControl conditionLong-term memoryBattery of testsDown syndromeAuditory processingVariety of individualsCognitive declineMemoryPoor performanceMajority of testsAlzheimer's diseaseAdultsIndividualsCognitionYears of ageDementiaDS individualsCharacteristic plaquesParticipantsSyndromeDiseaseProcessingPeopleAgePerformance