Protocol for a population-based molecular epidemiology study of tuberculosis transmission in a high HIV-burden setting: the Botswana Kopanyo study
Zetola N, Modongo C, Moonan P, Click E, Oeltmann J, Shepherd J, Finlay A, Basotli J, Bile E, Boyd R, Mbashi D, Fane O, Shin S, Surie D, Cowger V, Matsire O, Posey J, Serumola C, Tobias J. Protocol for a population-based molecular epidemiology study of tuberculosis transmission in a high HIV-burden setting: the Botswana Kopanyo study. BMJ Open 2016, 6: e010046. PMID: 27160840, PMCID: PMC4874111, DOI: 10.1136/bmjopen-2015-010046.Peer-Reviewed Original ResearchConceptsTB transmissionHIV infectionHigh HIV burden settingsPopulation-based molecular epidemiology studiesHIV burden settingsTuberculosis index casesAirborne droplet nucleiHigh rateMolecular epidemiology studiesMtb transmissionIndependent review boardTuberculosis transmissionUS CentersRecent transmissionHigh riskIndex caseLow prevalenceMTB isolatesParticipants' residencesEthical approvalEpidemiology studiesDisease controlHIVReview boardMycobacterium tuberculosis