2021
Association between Socioeconomic Status and Incidence of Community-Associated Clostridioides difficile Infection — United States, 2014–2015
Skrobarcek K, Mu Y, Ahern J, Basiliere E, Beldavs Z, Brousseau G, Dumyati G, Fridkin S, Holzbauer S, Johnston H, Kainer M, Meek J, Ocampo V, Parker E, Perlmutter R, Phipps E, Winston L, Guh A. Association between Socioeconomic Status and Incidence of Community-Associated Clostridioides difficile Infection — United States, 2014–2015. Clinical Infectious Diseases 2021, 73: 722-725. PMID: 33462596, PMCID: PMC8286972, DOI: 10.1093/cid/ciab042.Peer-Reviewed Original Research
2015
Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials
Baggs J, Yousey-Hindes K, Ashley ED, Meek J, Dumyati G, Cohen J, Wise ME, McDonald LC, Lessa FC. Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials. Vaccine 2015, 33: 6241-6249. PMID: 26450660, PMCID: PMC4702247, DOI: 10.1016/j.vaccine.2015.09.078.Peer-Reviewed Original ResearchConceptsEmerging Infections ProgramHigh-risk groupRisk groupsRisk scoreIndex hospitalizationHospital dischargeDerivation cohortVaccine trialsValidation cohortDifficile infectionCox proportional hazards modelRisk of CDIAcute care hospitalizationIdentification of patientsClostridium difficile infectionHospital discharge dataNumber of hospitalizationsLow-risk groupProportional hazards modelLarge academic centerAdmission diagnosisPrimary outcomeInpatient stayPatient populationPharmacy dataBurden of Clostridium difficile Infection in the United States
Lessa F, Mu Y, Bamberg W, Beldavs Z, Dumyati G, Dunn J, Farley M, Holzbauer S, Meek J, Phipps E, Wilson L, Winston L, Cohen J, Limbago B, Fridkin S, Gerding D, McDonald L. Burden of Clostridium difficile Infection in the United States. New England Journal Of Medicine 2015, 372: 825-834. PMID: 25714160, PMCID: PMC10966662, DOI: 10.1056/nejmoa1408913.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionDifficile infectionFirst recurrenceHealth care-associated infectionsCommunity-associated infectionsC. difficile infectionCare-associated infectionsPersons 65 yearsLaboratory-based surveillanceType 1 strainsNumber of deathsNational incidenceMolecular typingC. difficileInfectionIncidenceDeathUnited StatesRecurrenceGeographic areasSample of casesEstimated numberRegression modelsActive populationHealth
2014
Clostridium difficile Infection Among Children Across Diverse US Geographic Locations
Wendt J, Cohen J, Mu Y, Dumyati G, Dunn J, Holzbauer S, Winston L, Johnston H, Meek J, Farley M, Wilson L, Phipps E, Beldavs Z, Gerding D, McDonald L, Gould C, Lessa F. Clostridium difficile Infection Among Children Across Diverse US Geographic Locations. Pediatrics 2014, 133: 651-658. PMID: 24590748, PMCID: PMC10932476, DOI: 10.1542/peds.2013-3049.Peer-Reviewed Original ResearchMeSH KeywordsChild, PreschoolClostridioides difficileClostridium InfectionsFemaleHumansIncidenceInfantMaleUnited StatesConceptsClostridium difficile infectionAge groupsCDI incidenceDifficile infectionCommunity-associated casesProportion of casesYears of ageHealth care facilitiesYoung childrenSimilar disease severityUnnecessary antimicrobial useUS geographic areasHospital admissionClinical presentationCDI surveillanceOutpatient settingCDI casesC difficileEtiologic roleClinical dataSevere diseaseStool collectionCare facilitiesDisease severityCA casesVital signs: improving antibiotic use among hospitalized patients.
Fridkin S, Baggs J, Fagan R, Magill S, Pollack LA, Malpiedi P, Slayton R, Khader K, Rubin MA, Jones M, Samore MH, Dumyati G, Dodds-Ashley E, Meek J, Yousey-Hindes K, Jernigan J, Shehab N, Herrera R, McDonald L, Schneider A, Srinivasan A. Vital signs: improving antibiotic use among hospitalized patients. MMWR Morbidity And Mortality Weekly Report 2014, 63: 194-200. PMID: 24598596, PMCID: PMC4584728.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionAntibiotic prescribingAntibiotic useIncidence of CDIInpatient antibiotic useDays of therapyNational administrative databaseBroad-spectrum antibioticsHealth care providersAntibiotic-resistant infectionsHospitalized patientsSurgical wardsDifficile infectionImproved prescribingAdministrative databasesAntibiotic exposureIncorrect prescribingPrescribingPatientsHospitalPatient recordsPatient safetyU.S. hospitalsAntibiotic resistanceAntibiotics
2011
Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007 - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC
Hirshon JM, Thompson AD, Limbago B, McDonald LC, Bonkosky M, Heimer R, Meek J, Mai V, Braden C. Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007 - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2011, 17: 1946-1949. PMID: 22000379, PMCID: PMC3310666, DOI: 10.3201/eid1710.110069.Peer-Reviewed Original Research