2016
Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes
Hunter J, Mu Y, Dumyati G, Farley M, Winston L, Johnston H, Meek J, Perlmutter R, Holzbauer S, Beldavs Z, Phipps E, Dunn J, Cohen J, Avillan J, Stone N, Gerding D, McDonald L, Lessa F. Burden of Nursing Home-Onset Clostridium difficile Infection in the United States: Estimates of Incidence and Patient Outcomes. Open Forum Infectious Diseases 2016, 3: ofv196. PMID: 26798767, PMCID: PMC4719744, DOI: 10.1093/ofid/ofv196.Peer-Reviewed Original ResearchClostridium difficile infectionDifficile infectionPatient outcomesPopulation-based surveillanceAcute care settingAppropriate antibiotic useEstimates of incidenceMedian ageSubstantial morbidityPositive stoolsMedical recordsRisk factorsAdvanced ageAntibiotic useInfection preventionAntibiotic exposureHome residentsNational incidenceCare settingsPositive specimenNational estimatesIncidenceSpecimen collectionAgeStool
2015
Burden of Clostridium difficile Infection in the United States
Lessa F, Mu Y, Bamberg W, Beldavs Z, Dumyati G, Dunn J, Farley M, Holzbauer S, Meek J, Phipps E, Wilson L, Winston L, Cohen J, Limbago B, Fridkin S, Gerding D, McDonald L. Burden of Clostridium difficile Infection in the United States. New England Journal Of Medicine 2015, 372: 825-834. PMID: 25714160, PMCID: PMC10966662, DOI: 10.1056/nejmoa1408913.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionDifficile infectionFirst recurrenceHealth care-associated infectionsCommunity-associated infectionsC. difficile infectionCare-associated infectionsPersons 65 yearsLaboratory-based surveillanceType 1 strainsNumber of deathsNational incidenceMolecular typingC. difficileInfectionIncidenceDeathUnited StatesRecurrenceGeographic areasSample of casesEstimated numberRegression modelsActive populationHealth