2021
Trends in Precancerous Cervical Lesions by Area-Based Measures of Poverty, Race, and Ethnicity, Connecticut, 2008-2018
Brackney MM, Weinberger DM, Higgins K, Meek J, Niccolai LM. Trends in Precancerous Cervical Lesions by Area-Based Measures of Poverty, Race, and Ethnicity, Connecticut, 2008-2018. Public Health Reports 2021, 137: 1146-1152. PMID: 34727517, PMCID: PMC9574305, DOI: 10.1177/00333549211056300.Peer-Reviewed Original ResearchConceptsPrecancerous cervical lesionsAverage annual percentage changeCervical lesionsArea-based measuresPublic Health Disparities Geocoding ProjectAge groupsHuman papillomavirus vaccinationJoinpoint regression softwareAnnual percentage changeActive surveillance systemHPV vaccinationPapillomavirus vaccinationBody of evidenceIncidence rateSociodemographic characteristicsLesionsYoung womenAnnual declineIncidence dataPercentage changeCut pointsWomenVaccinationCensus tract levelSurveillance system
2020
Human Papillomavirus 16/18–Associated Cervical Lesions: Differences by Area-Based Measures of Race and Poverty
Brackney MM, Gargano JW, Hannagan SE, Meek J, Querec TD, Niccolai LM. Human Papillomavirus 16/18–Associated Cervical Lesions: Differences by Area-Based Measures of Race and Poverty. American Journal Of Preventive Medicine 2020, 58: e149-e157. PMID: 32001053, DOI: 10.1016/j.amepre.2019.12.003.Peer-Reviewed Original ResearchConceptsHuman papillomavirus 16/18Area-based measuresProportion of lesionsCervical lesionsMultivariable logistic regression modelingHuman papillomavirus vaccineLogistic regression modelingPapillomavirus vaccineHuman papillomavirusInsurance statusNew Haven CountyHealth outcomesCensus tract characteristicsSociodemographic characteristicsLesionsIndependent effectsRegression modelingWomenEarly declineSignificant declineEthnicity
2019
Missed Opportunities for HPV Vaccination Among Vaccine-Eligible Women with High Grade Cervical Lesions
Russ SM, Brackney M, Meek J, Niccolai LM. Missed Opportunities for HPV Vaccination Among Vaccine-Eligible Women with High Grade Cervical Lesions. Vaccine 2019, 37: 4262-4267. PMID: 31248688, DOI: 10.1016/j.vaccine.2019.06.061.Peer-Reviewed Original ResearchConceptsHigh-grade cervical lesionsVaccine-eligible womenHPV vaccinationHPV diagnosisProvider recommendationCervical lesionsLog-binomial analysisHuman papillomavirus vaccineCervical intraepithelial neoplasiaStatewide surveillance systemCochran-Armitage trend testSelf-reported barriersArmitage trend testEligible patientsChart reviewHPV vaccinePapillomavirus vaccineVaccination statusCIN 2Intraepithelial neoplasiaVaccine eligibilityPatient interviewsVaccine historyNew Haven CountyVaccination
2017
Declines in Human Papillomavirus (HPV)–Associated High-Grade Cervical Lesions After Introduction of HPV Vaccines in Connecticut, United States, 2008–2015
Niccolai LM, Meek JI, Brackney M, Hadler JL, Sosa LE, Weinberger DM. Declines in Human Papillomavirus (HPV)–Associated High-Grade Cervical Lesions After Introduction of HPV Vaccines in Connecticut, United States, 2008–2015. Clinical Infectious Diseases 2017, 65: 884-889. PMID: 28520854, DOI: 10.1093/cid/cix455.Peer-Reviewed Original ResearchConceptsCervical cancer screeningCervical lesionsRisk behaviorsHPV vaccinationVaccination coverageHuman papillomavirusCancer screeningBirth cohortHigh-grade cervical lesionsHPV vaccination coverageRates of CIN2Cervical intraepithelial neoplasiaHigh-grade lesionsSexual risk behaviorsSignificant declineHPV vaccineVaccine impactIntraepithelial neoplasiaCervical cancerRisk factorsSurveillance periodSimilar epidemiologyChlamydia trachomatisCohort patternsNegative binomial regression
2015
Monitoring Effect of Human Papillomavirus Vaccines in US Population, Emerging Infections Program, 2008–2012 - Volume 21, Number 9—September 2015 - Emerging Infectious Diseases journal - CDC
Hariri S, Markowitz LE, Bennett NM, Niccolai LM, Schafer S, Bloch K, Park IU, Scahill MW, Julian P, Abdullah N, Levine D, Whitney E, Unger ER, Steinau M, Bauer HM, Meek J, Hadler J, Sosa L, Powell SE, Johnson ML, Group H. Monitoring Effect of Human Papillomavirus Vaccines in US Population, Emerging Infections Program, 2008–2012 - Volume 21, Number 9—September 2015 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2015, 21: 1557-1561. PMID: 26291379, PMCID: PMC4550135, DOI: 10.3201/eid2109.141841.Peer-Reviewed Original ResearchConceptsHuman papillomavirus vaccineYears of agePapillomavirus vaccineEmerging Infections Program sitesPopulation-based surveillance systemActive population-based surveillanceInfectious Diseases journal - CDCPre-invasive cervical lesionsHPV vaccination historyHPV type distributionPopulation-based surveillanceCervical intraepithelial neoplasiaAcute infectious diseasesRelevant clinical informationCatchment area populationHPV vaccinationHPV typesVaccination historyIntraepithelial neoplasiaCervical cancerCervical lesionsVaccine introductionWomen 18Clinical informationUS population
2013
Declining Rates of High-Grade Cervical Lesions in Young Women in Connecticut, 2008–2011
Niccolai LM, Julian PJ, Meek JI, McBride V, Hadler JL, Sosa LE. Declining Rates of High-Grade Cervical Lesions in Young Women in Connecticut, 2008–2011. Cancer Epidemiology Biomarkers & Prevention 2013, 22: 1446-1450. PMID: 23704476, DOI: 10.1158/1055-9965.epi-13-0272.Peer-Reviewed Original ResearchConceptsHigh-grade cervical lesionsCervical lesionsVaccine impactAge 21Young womenEarly vaccine impactHPV vaccine initiationCervical intraepithelial neoplasiaHuman papillomavirus type 16Women ages 21Women age 25Papillomavirus type 16Federal poverty levelCensus tract measuresFemales ages 21Vaccine initiationHPV vaccineIntraepithelial neoplasiaSurveillance registryCervical cancerCervical neoplasiaContinued surveillanceType 16Health disparitiesAge 25Individual and geographic disparities in human papillomavirus types 16/18 in high‐grade cervical lesions
Niccolai LM, Russ C, Julian PJ, Hariri S, Sinard J, Meek JI, McBride V, Markowitz LE, Unger ER, Hadler JL, Sosa LE. Individual and geographic disparities in human papillomavirus types 16/18 in high‐grade cervical lesions. Cancer 2013, 119: 3052-3058. PMID: 23661284, DOI: 10.1002/cncr.28038.Peer-Reviewed Original Research
2012
Human Papillomavirus Vaccination History Among Women With Precancerous Cervical Lesions
Mehta NR, Julian PJ, Meek JI, Sosa LE, Bilinski A, Hariri S, Markowitz LE, Hadler JL, Niccolai LM. Human Papillomavirus Vaccination History Among Women With Precancerous Cervical Lesions. Obstetrics And Gynecology 2012, 119: 575-581. PMID: 22353956, DOI: 10.1097/aog.0b013e3182460d9f.Peer-Reviewed Original ResearchConceptsHuman papillomavirus vaccination historyAbnormal cytology resultsPrecancerous cervical lesionsCervical lesionsHPV vaccineVaccination historyCytology resultsHigh-grade cervical lesionsPrivate insuranceMedical record reviewTiming of vaccinationHistory of vaccinationPublic health surveillanceAfrican American womenUnvaccinated womenUninsured womenRecord reviewSurveillance registryMore dosesMean ageProvider recommendationVaccination strategiesVaccinationHealth surveillanceLesions
2011
P1-S6.43 HPV vaccine coverage among high-risk women: racial and socioeconomic disparities and barriers
Niccola L, Mehta N, Julian P, Bilinski A, Sosa L, Meek J, Hariri S, Markowitz L, Hadler J. P1-S6.43 HPV vaccine coverage among high-risk women: racial and socioeconomic disparities and barriers. Sexually Transmitted Infections 2011, 87: a213. DOI: 10.1136/sextrans-2011-050108.267.Peer-Reviewed Original ResearchHPV vaccine coveragePrecancerous cervical lesionsSelf-reported barriersVaccine coverageHPV vaccineCervical cancerCervical lesionsHuman papillomavirusCommon self-reported barriersCommon self-reported reasonsAdequate vaccine coverageFemales ages 11Previous HPV infectionHigh-risk womenWomen ages 18Low-income womenBlack womenHPV vaccinationUnderinsured womenHPV infectionEligible womenUninsured womenHPV diagnosisHPV typesMedian age