Homez, a homeobox leucine zipper gene specific to the vertebrate lineage
Bayarsaihan D, Enkhmandakh B, Makeyev A, Greally JM, Leckman JF, Ruddle FH. Homez, a homeobox leucine zipper gene specific to the vertebrate lineage. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 10358-10363. PMID: 12925734, PMCID: PMC193566, DOI: 10.1073/pnas.1834010100.Peer-Reviewed Original ResearchConceptsLeucine zipper-like motifHomeobox-containing proteinLobe-finned fishesVertebrate homeobox genesFamily of genesLeucine zipper genesUnusual structural organizationZipper-like motifOverall protein structureVertebrate lineageComplementation modelZipper genePufferfish homologsHomeodomain sequencesMammalian sequencesMouse geneZHX familyMouse developmentAcidic domainHomeobox genesPhylogenetic analysisHomeodomain factorsGenomic analysisAtypical homeodomainHomezEpigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype
State MW, Greally JM, Cuker A, Bowers PN, Henegariu O, Morgan TM, Gunel M, DiLuna M, King RA, Nelson C, Donovan A, Anderson GM, Leckman JF, Hawkins T, Pauls DL, Lifton RP, Ward DC. Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 4684-4689. PMID: 12682296, PMCID: PMC153616, DOI: 10.1073/pnas.0730775100.Peer-Reviewed Original Research