Tic disorders: when habit forming neural systems form habits of their own?
Leckman JF, Yeh CB, Cohen DJ. Tic disorders: when habit forming neural systems form habits of their own? Journal Of The Chinese Medical Association 2001, 64: 669-92. PMID: 11922487.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTourette syndromeAttention-deficit/hyperactivity disorderBasal gangliaIntolerable side effectsSubgroup of patientsLong-term outcomesAlpha-adrenergic agentsMajor affective disordersSpecific brain circuitsNew therapeutic directionDeficit/hyperactivity disorderAutoimmune mechanismsEarly brain developmentComorbid conditionsAtypical neurolepticsClinical neuroscience researchClinical trialsPrevalent disorderChildhood onsetClinical careMarked impairmentSide effectsPharmacological techniquesAffective disorders