2009
The ageing athlete: screening prior to vigorous exertion in asymptomatic adults without known cardiovascular disease
Freeman J, Froelicher V, Ashley E. The ageing athlete: screening prior to vigorous exertion in asymptomatic adults without known cardiovascular disease. British Journal Of Sports Medicine 2009, 43: 696. PMID: 19734505, DOI: 10.1136/bjsm.2008.054783.Peer-Reviewed Original ResearchConceptsExercise ECG testingVigorous exercise programRisk factorsObservational studyECG testingCV eventsAsymptomatic patientsAsymptomatic menAsymptomatic adultsExercise programPrognostic valueExercise electrocardiogramCardiovascular diseaseMore CV risk factorsMultiple cardiac risk factorsAsymptomatic healthy womenIncident CV eventsCardiac risk factorsCV risk factorsProspective observational studySimilar prognostic valueExercise ECG testMore conclusive dataRisk factor exposureElderly patientsShould the exercise ECG be used to screen for sudden cardiac death?
Freeman J, Ashley EA, Froelicher V. Should the exercise ECG be used to screen for sudden cardiac death? European Heart Journal 2009, 30: 528-529. PMID: 19201762, DOI: 10.1093/eurheartj/ehp029.Peer-Reviewed Original ResearchStatin Use and Ventricular Arrhythmias During Clinical Treadmill Testing
DEWEY FE, PEREZ M, HADLEY D, FREEMAN JV, WANG P, ASHLEY EA, MYERS J, FROELICHER VF. Statin Use and Ventricular Arrhythmias During Clinical Treadmill Testing. Journal Of Cardiovascular Electrophysiology 2009, 20: 193-199. PMID: 18775041, DOI: 10.1111/j.1540-8167.2008.01284.x.Peer-Reviewed Original ResearchConceptsFrequent premature ventricular complexesPremature ventricular complexesStatin useVentricular arrhythmiasCoronary diseaseTreadmill testingLower oddsExercise-induced ventricular arrhythmiasPropensity-adjusted logistic regressionsVA Palo Alto Health Care SystemClinical treadmill testingPrior coronary diseaseExercise treadmill testingExercise-induced anginaCoronary artery diseasePropensity score adjustmentHealth care systemPVC rateExercise capacityArtery diseaseAdverse prognosisFree patientsReduced oddsVentricular complexesStudy population
2008
Prediction of Cardiovascular Death using a Novel Heart Rate Recovery Parameter
HADLEY DM, DEWEY FE, FREEMAN JV, MYERS JN, FROELICHER VF. Prediction of Cardiovascular Death using a Novel Heart Rate Recovery Parameter. Medicine & Science In Sports & Exercise 2008, 40: 1072-1079. PMID: 18460999, DOI: 10.1249/mss.0b013e318167665a.Peer-Reviewed Original ResearchConceptsDuke treadmill scoreHeart rate recoveryHR increaseCV mortalityVagal toneCardiovascular causesCardiovascular deathPeak exerciseLowest tertileTreadmill scoreCox analysisClinical parametersMaximal exerciseSympathetic influencesExercise indexRate recoveryVagal influencePrognostic measurementMortalityPatientsRecovery variablesNormal scoresScoresExerciseRecovery parameters
2007
Novel predictor of prognosis from exercise stress testing: Heart rate variability response to the exercise treadmill test
Dewey FE, Freeman JV, Engel G, Oviedo R, Abrol N, Ahmed N, Myers J, Froelicher VF. Novel predictor of prognosis from exercise stress testing: Heart rate variability response to the exercise treadmill test. American Heart Journal 2007, 153: 281-288. PMID: 17239690, DOI: 10.1016/j.ahj.2006.11.001.Peer-Reviewed Original ResearchConceptsHeart rate variabilitySquare successive differenceCardiovascular mortalityPrognostic powerHF powerExercise treadmill testingRoot mean square successive differenceFrequency-domain HRV analysisExercise stress testingExercise treadmill testMortality end pointsSuccessive differencesStandard exercise testingHeart rate variability responsesMinutes of recoveryStrongest predictorLow-frequency powerMean square successive differenceHigh-frequency powerR interval dataCardiovascular deathCause mortalityPeak exerciseClinical factorsExercise testing