2018
Neurocognitive correlates of treatment response in children with Tourette's Disorder
Chang SW, McGuire JF, Walkup JT, Woods DW, Scahill L, Wilhelm S, Peterson AL, Dziura J, Piacentini J. Neurocognitive correlates of treatment response in children with Tourette's Disorder. Psychiatry Research 2018, 261: 464-472. PMID: 29407718, PMCID: PMC5809184, DOI: 10.1016/j.psychres.2017.12.066.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntipsychotic AgentsAttention Deficit Disorder with HyperactivityBehavior TherapyChildFemaleHumansInhibition, PsychologicalLearningMaleMemory, Short-TermMental Status and Dementia TestsTourette SyndromeTreatment OutcomeConceptsAttention deficit hyperactivity disorderBehavior therapyNeurocognitive functioningCo-occurring attention-deficit hyperactivity disorderPerformance speedTourette's disorderBrief neurocognitive batteryDeficit hyperactivity disorderBehavior therapy groupSmall negative associationNeurocognitive predictorsNeurocognitive correlatesCognitive functioningNeurocognitive batteryHabit learningPositive treatment responseHyperactivity disorderMotor inhibitionGroup differencesNeurocognitive statusFunctioningGreater baselineMemoryYouthNegative association
2017
Moderators and predictors of response to behavior therapy for tics in Tourette syndrome
Sukhodolsky DG, Woods DW, Piacentini J, Wilhelm S, Peterson AL, Katsovich L, Dziura J, Walkup JT, Scahill L. Moderators and predictors of response to behavior therapy for tics in Tourette syndrome. Neurology 2017, 88: 1029-1036. PMID: 28202705, PMCID: PMC5384839, DOI: 10.1212/wnl.0000000000003710.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAttention Deficit Disorder with HyperactivityBehavior TherapyChildFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePredictive Value of TestsTicsTourette SyndromeTreatment OutcomeYoung AdultConceptsPredictors of responseChronic tic disorderTic reductionTic disordersPsychiatric disordersYale Global Tic Severity Scale-Total Tic ScoreTic severityTourette syndromeClinical Global Impressions-Improvement scoreCo-occurring psychiatric disordersAnxiety disordersSubgroup of patientsTotal tic scoreMain outcome measuresPredictors of outcomeBehavior therapyComprehensive Behavioral InterventionAttention-deficit/hyperactivity disorderPremonitory urge severityReduction of ticsCo-occurring attention-deficit/hyperactivity disorderGreater tic severityTIC characteristicsTic improvementClinical characteristics
2016
Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder
Lecavalier L, Smith T, Johnson C, Bearss K, Swiezy N, Aman MG, Sukhodolsky DG, Deng Y, Dziura J, Scahill L. Moderators of Parent Training for Disruptive Behaviors in Young Children with Autism Spectrum Disorder. Research On Child And Adolescent Psychopathology 2016, 45: 1235-1245. PMID: 27917460, PMCID: PMC5459681, DOI: 10.1007/s10802-016-0233-x.Peer-Reviewed Original ResearchMeSH KeywordsAnxietyAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild BehaviorChild, PreschoolComorbidityEducation, NonprofessionalFamily TherapyFemaleHumansMaleProblem BehaviorConceptsHome Situations QuestionnaireAutism spectrum disorderParent education programAttention deficit hyperactivity disorderParent trainingAberrant Behavior Checklist-Irritability subscaleSpectrum disorderClinical Global Impressions-Improvement scaleDisruptive behaviorOppositional defiant disorder symptomsASD symptom severityLow anxiety groupDeficit hyperactivity disorderYoung childrenADHD groupASD severityHyperactivity disorderAnxiety groupDisorder symptomsPotential moderatorsSituations QuestionnaireNoncompliant behaviorAge 3ModeratorSymptom severity
2006
AProspective Open Trial of Guanfacine in Children with Pervasive Developmental Disorders
Scahill L, Aman MG, McDougle CJ, McCracken JT, Tierney E, Dziura J, Arnold LE, Posey D, Young C, Shah B, Ghuman J, Ritz L, Vitiello B. AProspective Open Trial of Guanfacine in Children with Pervasive Developmental Disorders. Journal Of Child And Adolescent Psychopharmacology 2006, 16: 589-598. PMID: 17069547, DOI: 10.1089/cap.2006.16.589.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenergic alpha-AgonistsAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildChild Development Disorders, PervasiveChild, PreschoolFemaleGuanfacineHumansMaleMethylphenidatePersonality AssessmentPilot ProjectsProspective StudiesTreatment FailureTreatment OutcomeConceptsOpen-label trialAberrant Behavior ChecklistPervasive developmental disorderClinical Global Impression-ImprovementHyperactivity subscaleEfficacy of guanfacinePlacebo-controlled trialCommon adverse effectsWeeks of treatmentTreatment of hyperactivityDevelopmental disordersBlood pressureOpen trialMean ageSleep disturbancesCommon complaintClinical practiceGuanfacineHyperactivityPilot studyAdverse effectsTrialsBehavior ChecklistChildrenMethylphenidate