2022
Gender Differences in Guideline-Directed Medical Therapy for Cardiovascular Disease Among Young Veterans
Dhruva SS, Dziura J, Bathulapalli H, Rosman L, Gaffey AE, Davis MB, Brandt CA, Haskell SG. Gender Differences in Guideline-Directed Medical Therapy for Cardiovascular Disease Among Young Veterans. Journal Of General Internal Medicine 2022, 37: 806-815. PMID: 36042086, PMCID: PMC9481764, DOI: 10.1007/s11606-022-07595-1.Peer-Reviewed Original ResearchConceptsGuideline-directed medical therapyIncident coronary artery diseaseCoronary artery diseaseHeart failureMedical therapyCardiovascular diseaseWomen veteransDiagnosis of HFAldosterone system inhibitorsIncident heart failureAdverse cardiovascular outcomesClinical practice guidelinesRisk of mortalityLevel of evidenceYounger women veteransHF medicationsMultiple pharmacotherapiesAntiplatelet therapyCardiovascular outcomesYounger average ageArtery diseaseCVD careGuideline recommendationsSystem inhibitorsAdverse outcomes
2021
Variations in Quality of Care by Sex and Social Determinants of Health Among Younger Adults With Acute Myocardial Infarction in the US and Canada
Raparelli V, Pilote L, Dang B, Behlouli H, Dziura JD, Bueno H, D’Onofrio G, Krumholz HM, Dreyer RP. Variations in Quality of Care by Sex and Social Determinants of Health Among Younger Adults With Acute Myocardial Infarction in the US and Canada. JAMA Network Open 2021, 4: e2128182. PMID: 34668947, PMCID: PMC8529414, DOI: 10.1001/jamanetworkopen.2021.28182.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionQuality of careHealth care systemYoung adultsFemale sexMyocardial infarctionCare systemHospital careSocial determinantsRetrospective cohort analysisLow qualityAdverse SDOHLowest tertileReadmission ratesMore patientsPostacute careAMI careOutpatient careCare scoresHigh prevalenceCohort analysisLarge cohortMAIN OUTCOMESDOHHospitalSex Differences in Use of a Clinical Complexity Measure to Predict Primary Care Utilization
Haskell SG, Han L, Abel EA, Bastian L, Driscoll M, Dziura J, Burg MM, Skanderson M, Brandt CA. Sex Differences in Use of a Clinical Complexity Measure to Predict Primary Care Utilization. Journal Of Women's Health 2021, 31: 71-78. PMID: 34388023, DOI: 10.1089/jwh.2021.0103.Peer-Reviewed Original ResearchConceptsPrimary care utilizationCare utilizationWomen veteransCare Assessment Need (CAN) scoreComplex high-risk patientsHigh-risk patientsRisk stratification toolPotential confounding factorsCorporate Data WarehouseSex differencesVA careVisit utilizationCare coordinationHigher oddsReproductive healthConfounding factorsVeterans AffairsPsychosocial variablesStrong associationQuintileWomenNeed scoresMenVeteransGood predictive accuracyBaseline Characteristics from the Women Veterans Cohort Study: Gender Differences and Similarities in Health and Healthcare Utilization
Gaffey AE, Burg MM, Rosman L, Portnoy GA, Brandt CA, Cavanagh CE, Skanderson M, Dziura J, Mattocks KM, Bastian LA, Haskell SG. Baseline Characteristics from the Women Veterans Cohort Study: Gender Differences and Similarities in Health and Healthcare Utilization. Journal Of Women's Health 2021, 30: 944-955. PMID: 33439756, PMCID: PMC8290312, DOI: 10.1089/jwh.2020.8732.Peer-Reviewed Original ResearchConceptsWomen Veterans Cohort StudyCardiovascular risk factorsVeterans Health AdministrationRisk factorsHealthcare utilizationWomen veteransCohort studyHealth outcomesNontraditional cardiovascular risk factorsTraditional cardiovascular risk factorsUnique healthcareMental healthSingle-site painVHA healthcare systemVHA medical centersVeterans Affairs (VA) careHealth risk factorsOutside health servicesPosttraumatic stress disorder (PTSD) symptomsMultisite painBaseline characteristicsPsychosocial comorbiditiesChronic painCardiovascular diseaseMedical CenterAssociation of Race/Ethnicity and Other Demographic Characteristics With Use of Physical Restraints in the Emergency Department
Wong AH, Whitfill T, Ohuabunwa EC, Ray JM, Dziura JD, Bernstein SL, Taylor RA. Association of Race/Ethnicity and Other Demographic Characteristics With Use of Physical Restraints in the Emergency Department. JAMA Network Open 2021, 4: e2035241. PMID: 33492372, PMCID: PMC7835716, DOI: 10.1001/jamanetworkopen.2020.35241.Peer-Reviewed Original Research
2020
Incident Musculoskeletal Conditions Among Men and Women Veterans Returning From Deployment
Haskell SG, Brandt C, Bastian L, Driscoll M, Bathulapalli H, Dziura J. Incident Musculoskeletal Conditions Among Men and Women Veterans Returning From Deployment. Medical Care 2020, 58: 1082-1090. PMID: 32925458, DOI: 10.1097/mlr.0000000000001403.Peer-Reviewed Original ResearchConceptsMSK conditionsAnkle/footVeterans AffairsUpper extremityMen veteransClinical Modification diagnostic codesPercent of womenOperation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn VeteransMSK diagnosesCohort studyNinth RevisionUnadjusted ratesMusculoskeletal conditionsDiagnostic codesIncidence rateOperation New Dawn veteransFirst visitMusculoskeletal injuriesNew Dawn veteransInternational ClassificationWomen veteransLast deploymentWomenVeteransMen
2019
Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults
Rosman L, Sico JJ, Lampert R, Gaffey AE, Ramsey CM, Dziura J, Chui PW, Cavanagh CE, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults. Stroke 2019, 50: 2996-3003. PMID: 31619151, DOI: 10.1161/strokeaha.119.026854.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIncident transient ischemic attackPosttraumatic stress disorderEffects of PTSDIschemic strokeIncident strokeHealthcare utilizationIncidence of TIAStress disorderYoung adultsMiddle-aged veteransStroke risk factorsMultivariate Cox modelIschemic stroke riskAge-specific prevention strategiesVeterans Health AdministrationMiddle-aged adultsIschemic attackStroke riskPsychological factorsUnadjusted analysesRisk factorsEffect modificationCox modelPsychiatric disorders
2018
Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study
Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.Peer-Reviewed Original ResearchConceptsMI-CAD patientsNonobstructive coronary arteriesMI-CADYounger patientsClinical profileCoronary arteryMyocardial infarctionTraditional cardiac risk factorsAcute myocardial infarction patientsCardiac risk factorsGestational diabetes mellitusMyocardial infarction patientsTimes higher oddsMINOCA patientsSAQ qualityVIRGO StudyClinical characteristicsHypercoaguable stateDiabetes mellitusObstructive diseaseClinical outcomesInfarction patientsRisk factorsMINOCAPsychosocial status
2017
Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment
Haskell SG, Brandt C, Burg M, Bastian L, Driscoll M, Goulet J, Mattocks K, Dziura J. Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment. Medical Care 2017, 55: 948-955. PMID: 28984707, DOI: 10.1097/mlr.0000000000000801.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsCV risk factorsRisk factorsImpact of sexWomen veteransClinical Modification diagnostic codesIncident cardiovascular risk factorsPrimary care visitsCoronary artery diseaseElectronic health record dataRisk of obesityVeterans Health AdministrationIncident risk factorsHealth record dataMental health conditionsBlack womenNew International ClassificationCare visitsCohort studyArtery diseaseFemale sexDiagnostic codesIncidence rateProtective effectInternational Classification
2016
Incidence of Mental Health Diagnoses in Veterans of Operations Iraqi Freedom, Enduring Freedom, and New Dawn, 2001-2014.
Ramsey C, Dziura J, Justice AC, Altalib HH, Bathulapalli H, Burg M, Decker S, Driscoll M, Goulet J, Haskell S, Kulas J, Wang KH, Mattocks K, Brandt C. Incidence of Mental Health Diagnoses in Veterans of Operations Iraqi Freedom, Enduring Freedom, and New Dawn, 2001-2014. American Journal Of Public Health 2016, 107: 329-335. PMID: 27997229, PMCID: PMC5227942, DOI: 10.2105/ajph.2016.303574.Peer-Reviewed Original ResearchConceptsMental health diagnosesMajor depressive disorderPosttraumatic stress disorderHealth diagnosisIncidence rateDrug use disorder diagnosisIncident posttraumatic stress disorderOperation Iraqi FreedomAge 18Veterans Health Administration electronic health recordsDisorder diagnosisIncident bipolar disorderHigh-risk groupSociodemographic risk factorsAlcohol use disorder diagnosisMental health conditionsEnduring FreedomIraqi FreedomRace/ethnicityElectronic health recordsIncident schizophreniaRisk factorsDepressive disorderAge 45MDD diagnosis
2015
Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV
Becker WC, Gordon K, Jennifer Edelman E, Kerns RD, Crystal S, Dziura JD, Fiellin LE, Gordon AJ, Goulet JL, Justice AC, Fiellin DA. Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV. AIDS And Behavior 2015, 20: 679-686. PMID: 26384973, PMCID: PMC5006945, DOI: 10.1007/s10461-015-1197-5.Peer-Reviewed Original Research
2014
Sex Differences in Patient and Provider Response to Elevated Low-Density Lipoprotein Cholesterol
Haskell SG, Bathulapalli H, Pham T, Goulet J, Skanderson M, Driscoll M, Brandt C, Dziura J. Sex Differences in Patient and Provider Response to Elevated Low-Density Lipoprotein Cholesterol. Women's Health Issues 2014, 24: 575-580. PMID: 25213750, DOI: 10.1016/j.whi.2014.06.004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticholesteremic AgentsAttitude of Health PersonnelAttitude to HealthDyslipidemiasElectronic Health RecordsFemaleHealthcare DisparitiesHumansLipoproteins, LDLLogistic ModelsMaleMiddle AgedOdds RatioPractice Patterns, Physicians'Risk FactorsSex FactorsTreatment OutcomeUnited StatesConceptsCholesterol controlElevated LDLLow-density lipoprotein cholesterol controlElevated low-density lipoprotein cholesterolLow-density lipoprotein cholesterolProvider responsesAmerican Heart Association recommendationsLipid-lowering medicationsIschemic heart diseaseDiet/lifestyle modificationLifestyle modificationStatin therapyLipoprotein cholesterolPatient factorsPatient sexRisk womenClinical remindersHeart diseaseWomen patientsPatient responseTreatment goalsAssociation recommendationsLDL elevationsMedicationsWomen veterans
2009
Relationship of Serum S100B Levels and Intracranial Injury in Children With Closed Head Trauma
Bechtel K, Frasure S, Marshall C, Dziura J, Simpson C. Relationship of Serum S100B Levels and Intracranial Injury in Children With Closed Head Trauma. Pediatrics 2009, 124: e697-e704. PMID: 19786430, DOI: 10.1542/peds.2008-1493.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsBiomarkersBrain InjuriesCase-Control StudiesChildChild, PreschoolEmergency Service, HospitalFemaleFollow-Up StudiesFractures, BoneGlasgow Coma ScaleHead Injuries, ClosedHumansInjury Severity ScoreMaleMultiple TraumaNerve Growth FactorsPredictive Value of TestsProbabilityRetrospective StudiesRisk AssessmentS100 Calcium Binding Protein beta SubunitS100 ProteinsSex FactorsSurvival AnalysisTomography, X-Ray ComputedConceptsLong bone fracturesTime of venipunctureSerum S100B measurementClosed head traumaIntracranial injurySerum S100B levelsS100B levelsS100B measurementHead traumaUrban pediatric emergency departmentMean S100B levelsLevels of S100BPediatric emergency departmentYears of ageReferral hospitalSerum levelsEmergency departmentCranial CTSkeletal injuriesAnalysis of covarianceBone fracturesInjuryNonwhite childrenVenipunctureChildren