2022
Effect of the STRIDE fall injury prevention intervention on falls, fall injuries, and health‐related quality of life
Ganz DA, Yuan AH, Greene EJ, Latham NK, Araujo K, Siu AL, Magaziner J, Gurwitz JH, Wu AW, Alexander NB, Wallace RB, Greenspan SL, Rich J, Volpi E, Waring SC, Dykes PC, Ko F, Resnick NM, McMahon SK, Basaria S, Wang R, Lu C, Esserman D, Dziura J, Miller ME, Travison TG, Peduzzi P, Bhasin S, Reuben DB, Gill TM. Effect of the STRIDE fall injury prevention intervention on falls, fall injuries, and health‐related quality of life. Journal Of The American Geriatrics Society 2022, 70: 3221-3229. PMID: 35932279, PMCID: PMC9669115, DOI: 10.1111/jgs.17964.Peer-Reviewed Original ResearchConceptsHealth-related qualityHospital admissionEQ-5DMedical attentionLeast square mean changeFall injury riskSelf-reported fracturesFall-related fracturesFall-related outcomesIncidence rate ratiosInjury prevention interventionsPrimary care practicesReal-world effectivenessFall prevention studiesMeaningful clinical effectsGOV IDENTIFIERUsual careMultifactorial interventionClinical effectsEQ-VASPrevention StudyFall injuriesOlder adults ageMean changePrevention interventionsUser centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial
Melnick ER, Nath B, Dziura JD, Casey MF, Jeffery MM, Paek H, Soares WE, Hoppe JA, Rajeevan H, Li F, Skains RM, Walter LA, Patel MD, Chari SV, Platts-Mills TF, Hess EP, D'Onofrio G. User centered clinical decision support to implement initiation of buprenorphine for opioid use disorder in the emergency department: EMBED pragmatic cluster randomized controlled trial. The BMJ 2022, 377: e069271. PMID: 35760423, PMCID: PMC9231533, DOI: 10.1136/bmj-2021-069271.Peer-Reviewed Original ResearchConceptsOpioid use disorderUsual care armEmergency departmentUse disordersCare armPragmatic clusterClinical decision supportIntervention armRoutine emergency careSecondary implementation outcomesSeverity of withdrawalTertiary care centerClinical decision support toolInitiation of buprenorphineElectronic health record tasksElectronic health record workflowsRE-AIM frameworkElectronic health record platformsHealth record platformsClinical decision support systemElectronic health recordsVisit documentationTreatment of addictionUsual careAdult patients
2021
A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial
Esserman DA, Gill TM, Miller ME, Greene EJ, Dziura JD, Travison TG, Meng C, Peduzzi PN. A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial. Clinical Trials 2021, 18: 207-214. PMID: 33678038, PMCID: PMC8009806, DOI: 10.1177/1740774520980070.Peer-Reviewed Original ResearchConceptsPrimary outcome definitionUsual care armSerious fall injuriesMedical attentionOutcome definitionsFall injuriesElders trialCare armOvernight hospitalizationStudy powerCare managersIntervention effectsType 2 injuriesAscertainment biasAscertainment of outcomesInterim monitoring planUsual careHazard ratioPrimary outcomeIntervention armClinical trialsUnblinded observerClinical basisMulticomponent interventionAdditional fall
2020
Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well‐Being: The STRIDE Study
Gill TM, Bhasin S, Reuben DB, Latham NK, Araujo K, Ganz DA, Boult C, Wu AW, Magaziner J, Alexander N, Wallace RB, Miller ME, Travison TG, Greenspan SL, Gurwitz JH, Rich J, Volpi E, Waring SC, Manini TM, Min LC, Teresi J, Dykes PC, McMahon S, McGloin JM, Skokos EA, Charpentier P, Basaria S, Duncan PW, Storer TW, Gazarian P, Allore HG, Dziura J, Esserman D, Carnie MB, Hanson C, Ko F, Resnick NM, Wiggins J, Lu C, Meng C, Goehring L, Fagan M, Correa‐de‐Araujo R, Casteel C, Peduzzi P, Greene EJ. Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well‐Being: The STRIDE Study. Journal Of The American Geriatrics Society 2020, 69: 173-179. PMID: 33037632, PMCID: PMC8178516, DOI: 10.1111/jgs.16854.Peer-Reviewed Original ResearchConceptsSerious fall injuriesFall injuriesMultifactorial interventionPhysical functionOutcomes Measurement Information System (PROMIS) AnxietyLeast square mean changePragmatic cluster-randomized trialMean scoreCommunity-living personsIntervention group's mean scoreInjury prevention interventionsPrimary care practicesFalls Efficacy ScaleCluster-randomized trialUsual careElders StudyDisability InstrumentSTRIDE studyDepression ScaleMean changePrevention interventionsHigh riskCare practicesControl groupMeaningful improvementsD‐CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community‐Based Dementia Care Versus Usual Dementia Care
Reuben DB, Gill TM, Stevens A, Williamson J, Volpi E, Lichtenstein M, Jennings LA, Tan Z, Evertson L, Bass D, Weitzman L, Carnie M, Wilson N, Araujo K, Charpentier P, Meng C, Greene EJ, Dziura J, Liu J, Unger E, Yang M, Currie K, Lenoir KM, Green A, Abraham S, Vernon A, Samper‐Ternent R, Raji M, Hirst RM, Galloway R, Finney GR, Ladd I, Rahm AK, Borek P, Peduzzi P. D‐CARE: The Dementia Care Study: Design of a Pragmatic Trial of the Effectiveness and Cost Effectiveness of Health System–Based Versus Community‐Based Dementia Care Versus Usual Dementia Care. Journal Of The American Geriatrics Society 2020, 68: 2492-2499. PMID: 32949145, PMCID: PMC8086629, DOI: 10.1111/jgs.16862.Peer-Reviewed Original ResearchConceptsCommunity-based dementia careUsual careClinical trial sitesDementia careHealth systemCaregiver unmet needsNursing home placement ratesClinical health systemsDementia care specialistsUnit of randomizationQuality of lifeCost effectivenessDementia Care StudyPrimary outcomeClinical benefitSuperiority trialFunctional statusPragmatic trialCaregiver dyadsCare specialistsComprehensive careCaregiver distressCare studiesMedicare claimsNurse practitionersA Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries
Bhasin S, Gill TM, Reuben DB, Latham NK, Ganz DA, Greene EJ, Dziura J, Basaria S, Gurwitz JH, Dykes PC, McMahon S, Storer TW, Gazarian P, Miller ME, Travison TG, Esserman D, Carnie MB, Goehring L, Fagan M, Greenspan SL, Alexander N, Wiggins J, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace RB, Casteel C, Resnick NM, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Meng C, Allore H, Brawley BF, Eder R, McGloin JM, Skokos EA, Duncan PW, Baker D, Boult C, Correa-de-Araujo R, Peduzzi P. A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries. New England Journal Of Medicine 2020, 383: 129-140. PMID: 32640131, PMCID: PMC7421468, DOI: 10.1056/nejmoa2002183.Peer-Reviewed Original ResearchConceptsSerious fall injuriesFall injuriesIntervention groupControl groupUsual careMultifactorial interventionRate of hospitalizationPrimary care practicesCluster-randomized trialCommunity-dwelling adultsFirst-event analysisYears of ageHealth care systemRate of fallElectronic health recordsBaseline characteristicsPrimary outcomeRandomized trialsMean ageEfficacy trialsIndividualized planCare practicesInjuryMultifactorial strategyEvent rates
2017
Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods
Bhasin S, Gill TM, Reuben DB, Latham NK, Gurwitz JH, Dykes P, McMahon S, Storer TW, Duncan PW, Ganz DA, Basaria S, Miller ME, Travison TG, Greene EJ, Dziura J, Esserman D, Allore H, Carnie MB, Fagan M, Hanson C, Baker D, Greenspan SL, Alexander N, Ko F, Siu AL, Volpi E, Wu AW, Rich J, Waring SC, Wallace R, Casteel C, Magaziner J, Charpentier P, Lu C, Araujo K, Rajeevan H, Margolis S, Eder R, McGloin JM, Skokos E, Wiggins J, Garber L, Clauser SB, Correa-De-Araujo R, Peduzzi P. Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE): A Cluster-Randomized Pragmatic Trial of a Multifactorial Fall Injury Prevention Strategy: Design and Methods. The Journals Of Gerontology Series A 2017, 73: 1053-1061. PMID: 29045582, PMCID: PMC6037050, DOI: 10.1093/gerona/glx190.Peer-Reviewed Original ResearchConceptsSerious fall injuriesInjury prevention strategiesFall injuriesPragmatic trialHealth care systemUsual carePrevention strategiesControl groupOlder adultsCare systemMultifactorial risk assessmentCommunity-living personsEnhanced usual carePrimary outcome rateIndividualized care plansPrimary care practicesTarget sample sizeEvidence-based informationSecondary outcomesPrimary outcomeOutcome ratesComanagement modelFall preventionSTRIDE studyMedical attention
2016
Effective Translation of an Intensive Lifestyle Intervention for Hispanic Women With Prediabetes in a Community Health Center Setting
Van Name MA, Camp AW, Magenheimer EA, Li F, Dziura JD, Montosa A, Patel A, Tamborlane WV. Effective Translation of an Intensive Lifestyle Intervention for Hispanic Women With Prediabetes in a Community Health Center Setting. Diabetes Care 2016, 39: 525-531. PMID: 26908915, PMCID: PMC4806769, DOI: 10.2337/dc15-1899.Peer-Reviewed Original ResearchMeSH KeywordsAdiposityAdolescentAdultAgedBody Mass IndexChoice BehaviorCommunity Health CentersDiabetes Mellitus, Type 2ExerciseFeasibility StudiesFemaleFood PreferencesHispanic or LatinoHumansInsulinLife StyleMiddle AgedPilot ProjectsPrediabetic StateRisk FactorsSocioeconomic FactorsWaist CircumferenceWeight LossYoung AdultConceptsIntensive lifestyle interventionDiabetes Prevention ProgramCommunity health center settingUsual care groupType 2 diabetesHealth center settingHispanic womenILI groupLifestyle interventionCare groupOral glucose tolerance testCenter settingLow-income Hispanic womenWeight lossSimilar baseline weightGlucose tolerance testPercent body fatType of interventionCHC settingsDPP interventionsUsual careBaseline weightWaist circumferenceGlucose excursionsTolerance test
2010
Managing the Space between Visits: A Randomized Trial of Disease Management for Diabetes in a Community Health Center
Anderson DR, Christison-Lagay J, Villagra V, Liu H, Dziura J. Managing the Space between Visits: A Randomized Trial of Disease Management for Diabetes in a Community Health Center. Journal Of General Internal Medicine 2010, 25: 1116-1122. PMID: 20556536, PMCID: PMC2955486, DOI: 10.1007/s11606-010-1419-5.Peer-Reviewed Original ResearchConceptsCommunity health centersUsual careBlood pressureUnderserved patientsHealth centersPhysical activityControl groupDisease management supportTelephonic Disease ManagementDiastolic blood pressureIntake of fruitsBody mass indexType 2 diabetesDisease managementSignificant differencesLow socioeconomic statusDisease management programsSelf-management servicesBehavioral outcome measuresParticipantsAll patientsGlycemic controlPrimary outcomeSuch patientsLDL cholesterolMass index