2022
Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women
Gaffey AE, Rosman L, Sico JJ, Haskell SG, Brandt CA, Bathulapalli H, Han L, Dziura J, Skanderson M, Burg MM. Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women. Journal Of Hypertension 2022, 40: 2307-2315. PMID: 35983872, DOI: 10.1097/hjh.0000000000003267.Peer-Reviewed Original ResearchConceptsIncident hypertensionRisk factorsPsychiatric disordersMultivariate Cox proportional hazards modelVeterans Health Administration dataGreater riskCox proportional hazards modelTrauma-related psychiatric disordersMiddle-aged veteransCardiovascular risk factorsBaseline blood pressureElevated cardiovascular riskLarge prospective cohortHealth Administration dataMiddle-aged menProportional hazards modelSex-specific analysesPosttraumatic stress disorderMilitary sexual traumaCardiovascular riskCohort studyProspective cohortBlood pressureTreatment attenuatesCardiovascular impactAssociation of renalase with clinical outcomes in hospitalized patients with COVID-19
Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Association of renalase with clinical outcomes in hospitalized patients with COVID-19. PLOS ONE 2022, 17: e0264178. PMID: 35259186, PMCID: PMC8903289, DOI: 10.1371/journal.pone.0264178.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsRenalase levelsIntensive care unit admissionHospitalized COVID-19 patientsMean age 64 yearsCOVID-19Cox proportional hazards modelCare unit admissionPrimary composite outcomeRetrospective cohort studyUse of vasopressorsSevere COVID-19IL-6 levelsAge 64 yearsRisk of deathCOVID-19 subjectsInitial disease severityProportional hazards modelCOVID-19 diseasePlasma renalaseUnit admissionICU admissionCohort studyComposite outcomeCytokine levels
2021
Baseline Characteristics from the Women Veterans Cohort Study: Gender Differences and Similarities in Health and Healthcare Utilization
Gaffey AE, Burg MM, Rosman L, Portnoy GA, Brandt CA, Cavanagh CE, Skanderson M, Dziura J, Mattocks KM, Bastian LA, Haskell SG. Baseline Characteristics from the Women Veterans Cohort Study: Gender Differences and Similarities in Health and Healthcare Utilization. Journal Of Women's Health 2021, 30: 944-955. PMID: 33439756, PMCID: PMC8290312, DOI: 10.1089/jwh.2020.8732.Peer-Reviewed Original ResearchConceptsWomen Veterans Cohort StudyCardiovascular risk factorsVeterans Health AdministrationRisk factorsHealthcare utilizationWomen veteransCohort studyHealth outcomesNontraditional cardiovascular risk factorsTraditional cardiovascular risk factorsUnique healthcareMental healthSingle-site painVHA healthcare systemVHA medical centersVeterans Affairs (VA) careHealth risk factorsOutside health servicesPosttraumatic stress disorder (PTSD) symptomsMultisite painBaseline characteristicsPsychosocial comorbiditiesChronic painCardiovascular diseaseMedical Center
2020
Incident Musculoskeletal Conditions Among Men and Women Veterans Returning From Deployment
Haskell SG, Brandt C, Bastian L, Driscoll M, Bathulapalli H, Dziura J. Incident Musculoskeletal Conditions Among Men and Women Veterans Returning From Deployment. Medical Care 2020, 58: 1082-1090. PMID: 32925458, DOI: 10.1097/mlr.0000000000001403.Peer-Reviewed Original ResearchConceptsMSK conditionsAnkle/footVeterans AffairsUpper extremityMen veteransClinical Modification diagnostic codesPercent of womenOperation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn VeteransMSK diagnosesCohort studyNinth RevisionUnadjusted ratesMusculoskeletal conditionsDiagnostic codesIncidence rateOperation New Dawn veteransFirst visitMusculoskeletal injuriesNew Dawn veteransInternational ClassificationWomen veteransLast deploymentWomenVeteransMen
2019
Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults
Rosman L, Lampert R, Ramsey CM, Dziura J, Chui PW, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults. Journal Of The American Heart Association 2019, 8: e013741. PMID: 31564191, PMCID: PMC6806049, DOI: 10.1161/jaha.119.013741.Peer-Reviewed Original ResearchConceptsIncident atrial fibrillationPosttraumatic stress disorderMiddle-aged veteransAtrial fibrillationRisk factorsMultivariate Cox proportional hazards modelIncidence of AFCox proportional hazards modelStress disorderAF risk factorsCardiovascular risk factorsNew atrial fibrillationProspective cohort studyHigher overall incidenceVeterans Health AdministrationProportional hazards modelAcute psychological stressChronic stress syndromeCohort studyOverall incidenceAtrial tachycardiaLifestyle factorsAtrial flutterHealthcare useEffect modificationTrauma and Sexual Risk: Do Men and Women Veterans Differ?
Combellick JL, Dziura J, Portnoy GA, Mattocks KM, Brandt CA, Haskell SG. Trauma and Sexual Risk: Do Men and Women Veterans Differ? Women's Health Issues 2019, 29: s74-s82. PMID: 31253246, DOI: 10.1016/j.whi.2019.04.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAdult Survivors of Child AbuseAgedBullyingChildCohort StudiesCrime VictimsFemaleHumansIntimate Partner ViolenceMaleMiddle AgedMilitary PersonnelRisk FactorsRisk-TakingSexual BehaviorSurveys and QuestionnairesUnited StatesUnited States Department of Veterans AffairsVeteransVeterans HealthConceptsRisky sexual behaviorWomen veteransSexual behaviorSingle significant risk factorSignificant risk factorsWomen Veterans Cohort StudyVeterans Health AdministrationHistory of traumaRelated health outcomesCohort studyPredictive factorsRisk factorsMilitary-related traumaBinge drinkingMen veteransMilitary exposureHealth AdministrationHealth outcomesTrauma-related experiencesHealth servicesMultivariate analysisProtective factorsSexual riskTraumaAdditional risk
2018
“To Err Is Human” but Disclosure Must be Taught
Crimmins AC, Wong AH, Bonz JW, Tsyrulnik A, Jubanyik K, Dziura JD, Dodge KL, Evans LV. “To Err Is Human” but Disclosure Must be Taught. Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2018, 13: 107-116. PMID: 29346222, DOI: 10.1097/sih.0000000000000273.Peer-Reviewed Original ResearchConceptsError disclosurePractice guidelinesEmergency medicineMedical studentsMedical error disclosurePatient-centered careSenior EM residentsAttending EM physiciansLevels of clinical experienceIncreasing physician experienceProspective cohort studyLevel of trainingImmersive simulation scenariosEM physiciansEM residentsHealthcare providersSafe practice guidelinesPhysician experienceAttending physiciansAdverse eventsCohort studySuboptimal adherenceTotal scorePromote safetyProviders
2017
Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment
Haskell SG, Brandt C, Burg M, Bastian L, Driscoll M, Goulet J, Mattocks K, Dziura J. Incident Cardiovascular Risk Factors Among Men and Women Veterans After Return From Deployment. Medical Care 2017, 55: 948-955. PMID: 28984707, DOI: 10.1097/mlr.0000000000000801.Peer-Reviewed Original ResearchConceptsCardiovascular risk factorsCV risk factorsRisk factorsImpact of sexWomen veteransClinical Modification diagnostic codesIncident cardiovascular risk factorsPrimary care visitsCoronary artery diseaseElectronic health record dataRisk of obesityVeterans Health AdministrationIncident risk factorsHealth record dataMental health conditionsBlack womenNew International ClassificationCare visitsCohort studyArtery diseaseFemale sexDiagnostic codesIncidence rateProtective effectInternational ClassificationDepression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department
Kim Y, Soffler M, Paradise S, Jelani QU, Dziura J, Sinha R, Safdar B. Depression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department. American Heart Journal 2017, 191: 47-54. PMID: 28888269, DOI: 10.1016/j.ahj.2017.06.003.Peer-Reviewed Original ResearchConceptsRecurrent chest painCoronary artery diseaseAcute chest painChest painProspective cohort studyChest pain centerClinical Anxiety ScaleEmergency departmentPerceived Stress ScalePain centerCohort studyArtery diseaseNonobstructive coronary artery diseaseObstructive coronary artery diseaseChest pain recurrenceED chest painCardiac risk factorsCardiac stress testingPatient Health QuestionnaireSignificant independent predictorsStress testingMultivariable regression modelsPain recurrenceIndependent predictorsPrimary outcome
2015
Chest pain syndromes are associated with high rates of recidivism and costs in young United States Veterans
Safdar B, Dziura J, Bathulapalli H, Leslie DL, Skanderson M, Brandt C, Haskell SG. Chest pain syndromes are associated with high rates of recidivism and costs in young United States Veterans. BMC Primary Care 2015, 16: 88. PMID: 26202799, PMCID: PMC4511555, DOI: 10.1186/s12875-015-0287-9.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseUnexplained chest painChest painUCP patientsCAD patientsArtery diseaseRisk factorsReturn visitsSpecific ICD-9 codesVeterans AffairsChest pain syndromeRecurrent chest painReference groupRetrospective cohort studyEvidence-based guidelinesICD-9 codesUnited States veteransDirect total costCAD cohortCause deathCardiac painPain syndromeCohort studyCox regressionEmergency department
2014
The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations
Lang SM, Syed MA, Dziura J, Rocco E, Kirshbom P, Bhandari V, Giuliano JS. The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations. The Annals Of Thoracic Surgery 2014, 98: 1699-1704. PMID: 25258157, PMCID: PMC4253712, DOI: 10.1016/j.athoracsur.2014.06.053.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionModified ultrafiltrationUnit admissionCardiopulmonary bypassAngpt-2Interleukin-8Proinflammatory mediatorsClinical benefitAngpt-2 concentrationsInterleukin-10 levelsProspective cohort studySystemic inflammatory responseChildren 18 yearsEnzyme-linked immunosorbentCohort studyAntiinflammatory mediatorsInterleukin-10Inflammatory responseAngiopoietin-2Angpt-1Cardiothoracic operationsPatient's bloodAdmissionCytokine removalElevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients
Safdar B, Bezek SK, Sinusas AJ, Russell RR, Klein MR, Dziura JD, D’onofrio G. Elevated CK-MB with a Normal Troponin Does Not Predict 30-Day Adverse Cardiac Events in Emergency Department Chest Pain Observation Unit Patients. Critical Pathways In Cardiology A Journal Of Evidence-Based Medicine 2014, 13: 14-19. PMID: 24526146, DOI: 10.1097/hpc.0000000000000001.Peer-Reviewed Original ResearchConceptsAdverse cardiac eventsCPU patientsNormal troponinAdverse eventsCardiac eventsMultiple logistic regression modelComposite adverse eventsElevated creatinine kinaseObservation unit patientsSerial troponin testingStandardized chart reviewRetrospective cohort studyAcute coronary syndromeNational Death RegistryCoronary artery diseaseLogistic regression modelsPositive troponinPrior CADRenal insufficientCoronary syndromeHemodynamic instabilityChart reviewCohort studyDeath RegistryIschemic electrocardiogram
2004
Estimated change in physical activity level (PAL) and prediction of 5-year weight change in men: the Aerobics Center Longitudinal Study
Di Pietro L, Dziura J, Blair SN. Estimated change in physical activity level (PAL) and prediction of 5-year weight change in men: the Aerobics Center Longitudinal Study. International Journal Of Obesity 2004, 28: 1541-1547. PMID: 15543159, DOI: 10.1038/sj.ijo.0802821.Peer-Reviewed Original ResearchConceptsDaily physical activity levelsPhysical activity levelsAverage daily physical activity levelsAerobics Center Longitudinal StudyLow physical activity levelsWeight gainThird examinationWeight changeBody weightClinic-based cohort studySame physical activity levelDaily leisure-time physical activityLeisure-time physical activityActivity levelsLongitudinal studyCohort studyCooper ClinicBrisk walkingHealthy menPhysical activityMedical examinationWeight lossRegression modelingMenExamination