2001
Analysis of Risk Factors for Fatal Rocky Mountain Spotted Fever: Evidence for Superiority of Tetracyclines for Therapy
Holman R, Paddock C, Curns A, Krebs J, McQuiston J, Childs J. Analysis of Risk Factors for Fatal Rocky Mountain Spotted Fever: Evidence for Superiority of Tetracyclines for Therapy. The Journal Of Infectious Diseases 2001, 184: 1437-1444. PMID: 11709786, DOI: 10.1086/324372.Peer-Reviewed Original ResearchConceptsRisk factorsFatal Rocky Mountain Spotted FeverRocky Mountain Spotted FeverOnset of symptomsCase fatality rateTetracycline-class antibioticsPrimary therapyClinical characteristicsOlder patientsAppropriate therapyRMSF casesNonfatal casesNational surveillanceHigh riskSpotted FeverPatientsEffective antibioticsTherapyDeathFeverAntibioticsTreatmentSymptomsFactorsDisease
2000
Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics
Standaert S, Yu T, Scott M, Childs J, Paddock C, Nicholson W, Singleton J, Blaser M. Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics. The Journal Of Infectious Diseases 2000, 181: 1082-1088. PMID: 10720534, DOI: 10.1086/315346.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionE. chaffeensisCerebrospinal fluid specimensCultures of bloodHigh diagnostic yieldEhrlichia chaffeensisPrimary isolationFebrile illnessDiagnostic titerBlood isolatesDiagnostic yieldTick exposureSame patientCerebrospinal fluidPatientsFluid specimensDiagnostic testsFrequent isolationBloodChain reactionChaffeensisInfectionMolecular characteristicsMolecular analysisIsolatesRocky Mountain spotted fever in the United States, 1993-1996.
Treadwell T, Holman R, Clarke M, Krebs J, Paddock C, Childs J. Rocky Mountain spotted fever in the United States, 1993-1996. American Journal Of Tropical Medicine And Hygiene 2000, 63: 21-6. PMID: 11357990, DOI: 10.4269/ajtmh.2000.63.21.Peer-Reviewed Original Research
1999
An outbreak of acute bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998.
Ellis B, Rotz L, Leake J, Samalvides F, Bernable J, Ventura G, Padilla C, Villaseca P, Beati L, Regnery R, Childs J, Olson J, Carrillo C. An outbreak of acute bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998. American Journal Of Tropical Medicine And Hygiene 1999, 61: 344-9. PMID: 10463692, DOI: 10.4269/ajtmh.1999.61.344.Peer-Reviewed Original ResearchHidden Mortality Attributable to Rocky Mountain Spotted Fever: Immunohistochemical Detection of Fatal, Serologically Unconfirmed Disease
Paddock C, Greer P, Ferebee T, Singleton J, McKechnie D, Treadwell T, Krebs J, Clarke M, Holman R, Olson J, Childs J, Zaki S. Hidden Mortality Attributable to Rocky Mountain Spotted Fever: Immunohistochemical Detection of Fatal, Serologically Unconfirmed Disease. The Journal Of Infectious Diseases 1999, 179: 1469-1476. PMID: 10228069, DOI: 10.1086/314776.Peer-Reviewed Original ResearchConceptsCase fatality ratioDiagnosis of RMSFIHC stainingRocky Mountain Spotted FeverLaboratory-confirmed casesAcute-phase seraTickborne infectionHidden mortalityIgM antibodiesDiagnostic titerPolymerase chain reactionIHC findingsPatient seraSerologic assaysImmunohistochemical stainingSpotted FeverImmunohistochemical detectionFatal diseasePatientsDisease controlIndirect immunofluorescenceNotifiable diseaseDiseaseUnderestimates of mortalityTissue samplesFamily Cluster of Rocky Mountain Spotted Fever
Jones T, Craig A, Paddock C, McKechnie D, Childs J, Zaki S, Schaffner W. Family Cluster of Rocky Mountain Spotted Fever. Clinical Infectious Diseases 1999, 28: 853-859. PMID: 10825050, DOI: 10.1086/515213.Peer-Reviewed Original Research
1998
Epidemiology of Rodent Bites and Prediction of Rat Infestation in New York City
Childs J, McLafferty S, Sadek R, Miller G, Khan A, DuPree E, Advani R, Mills J, Glass G. Epidemiology of Rodent Bites and Prediction of Rat Infestation in New York City. American Journal Of Epidemiology 1998, 148: 78-87. PMID: 9663407, DOI: 10.1093/oxfordjournals.aje.a009563.Peer-Reviewed Original Research