2001
Analysis of Risk Factors for Fatal Rocky Mountain Spotted Fever: Evidence for Superiority of Tetracyclines for Therapy
Holman R, Paddock C, Curns A, Krebs J, McQuiston J, Childs J. Analysis of Risk Factors for Fatal Rocky Mountain Spotted Fever: Evidence for Superiority of Tetracyclines for Therapy. The Journal Of Infectious Diseases 2001, 184: 1437-1444. PMID: 11709786, DOI: 10.1086/324372.Peer-Reviewed Original ResearchConceptsRisk factorsFatal Rocky Mountain Spotted FeverRocky Mountain Spotted FeverOnset of symptomsCase fatality rateTetracycline-class antibioticsPrimary therapyClinical characteristicsOlder patientsAppropriate therapyRMSF casesNonfatal casesNational surveillanceHigh riskSpotted FeverPatientsEffective antibioticsTherapyDeathFeverAntibioticsTreatmentSymptomsFactorsDisease
2000
Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics
Standaert S, Yu T, Scott M, Childs J, Paddock C, Nicholson W, Singleton J, Blaser M. Primary Isolation of Ehrlichia chaffeensis from Patients with Febrile Illnesses: Clinical and Molecular Characteristics. The Journal Of Infectious Diseases 2000, 181: 1082-1088. PMID: 10720534, DOI: 10.1086/315346.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionE. chaffeensisCerebrospinal fluid specimensCultures of bloodHigh diagnostic yieldEhrlichia chaffeensisPrimary isolationFebrile illnessDiagnostic titerBlood isolatesDiagnostic yieldTick exposureSame patientCerebrospinal fluidPatientsFluid specimensDiagnostic testsFrequent isolationBloodChain reactionChaffeensisInfectionMolecular characteristicsMolecular analysisIsolatesRocky Mountain spotted fever in the United States, 1993-1996.
Treadwell T, Holman R, Clarke M, Krebs J, Paddock C, Childs J. Rocky Mountain spotted fever in the United States, 1993-1996. American Journal Of Tropical Medicine And Hygiene 2000, 63: 21-6. PMID: 11357990, DOI: 10.4269/ajtmh.2000.63.21.Peer-Reviewed Original Research
1999
An outbreak of acute bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998.
Ellis B, Rotz L, Leake J, Samalvides F, Bernable J, Ventura G, Padilla C, Villaseca P, Beati L, Regnery R, Childs J, Olson J, Carrillo C. An outbreak of acute bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998. American Journal Of Tropical Medicine And Hygiene 1999, 61: 344-9. PMID: 10463692, DOI: 10.4269/ajtmh.1999.61.344.Peer-Reviewed Original ResearchHidden Mortality Attributable to Rocky Mountain Spotted Fever: Immunohistochemical Detection of Fatal, Serologically Unconfirmed Disease
Paddock C, Greer P, Ferebee T, Singleton J, McKechnie D, Treadwell T, Krebs J, Clarke M, Holman R, Olson J, Childs J, Zaki S. Hidden Mortality Attributable to Rocky Mountain Spotted Fever: Immunohistochemical Detection of Fatal, Serologically Unconfirmed Disease. The Journal Of Infectious Diseases 1999, 179: 1469-1476. PMID: 10228069, DOI: 10.1086/314776.Peer-Reviewed Original ResearchConceptsCase fatality ratioDiagnosis of RMSFIHC stainingRocky Mountain Spotted FeverLaboratory-confirmed casesAcute-phase seraTickborne infectionHidden mortalityIgM antibodiesDiagnostic titerPolymerase chain reactionIHC findingsPatient seraSerologic assaysImmunohistochemical stainingSpotted FeverImmunohistochemical detectionFatal diseasePatientsDisease controlIndirect immunofluorescenceNotifiable diseaseDiseaseUnderestimates of mortalityTissue samplesSerologic Testing for Human Granulocytic Ehrlichiosis at a National Referral Center
Comer J, Nicholson W, Olson J, Childs J. Serologic Testing for Human Granulocytic Ehrlichiosis at a National Referral Center. Journal Of Clinical Microbiology 1999, 37: 558-564. PMID: 9986812, PMCID: PMC84468, DOI: 10.1128/jcm.37.3.558-564.1999.Peer-Reviewed Original ResearchConceptsHGE agentSerum samplesNational referral centerE. chaffeensis antigenSpecific etiologic agentState health departmentsE. chaffeensisHuman granulocytic ehrlichiosis (HGE) agentHuman granulocytic ehrlichiosisHuman monocytic ehrlichiosisReferral centerSerologic testingEhrlichial antigenAverage ageHealth departmentsHuman ehrlichiosisPatientsEtiologic agentProbable casesHigh titersIll individualsGranulocytic ehrlichiosisDisease controlIndirect immunofluorescenceMonocytic ehrlichiosis
1998
Epidemiology of Rodent Bites and Prediction of Rat Infestation in New York City
Childs J, McLafferty S, Sadek R, Miller G, Khan A, DuPree E, Advani R, Mills J, Glass G. Epidemiology of Rodent Bites and Prediction of Rat Infestation in New York City. American Journal Of Epidemiology 1998, 148: 78-87. PMID: 9663407, DOI: 10.1093/oxfordjournals.aje.a009563.Peer-Reviewed Original Research
1995
Rabies surveillance in the United States during 1994.
Krebs J, Strine T, Smith J, Rupprecht C, Childs J. Rabies surveillance in the United States during 1994. Journal Of The American Veterinary Medical Association 1995, 207: 1562-75. PMID: 7493894, DOI: 10.2460/javma.1995.207.12.1562.Peer-Reviewed Original ResearchCluster of five children with acute encephalopathy associated with cat-scratch disease in South Florida
NOAH D, BRESEE J, GORENSEK M, ROONEY J, CRESANTA J, REGNERY R, WONG J, DEL TORO J, OLSON J, CHILDS J. Cluster of five children with acute encephalopathy associated with cat-scratch disease in South Florida. The Pediatric Infectious Disease Journal 1995, 14: 866-869. PMID: 8584313, DOI: 10.1097/00006454-199510000-00009.Peer-Reviewed Original ResearchConceptsCat-scratch diseaseAcute encephalopathyEvaluation of childrenIndirect fluorescent antibodyRegional lymphadenopathyStatus epilepticusSingle hospitalEncephalopathy casesBartonella henselaeEncephalopathyB. henselaeFocal clustersCausative agentFluorescent antibodyStray catsDiseaseChildrenAntibodiesHenselaeHigher proportionCatsLymphadenopathyEpilepticusEncephalitisPatients