1999
Molecular Cloning and Characterization of the Ehrlichia chaffeensis Variable-Length PCR Target: an Antigen-Expressing Gene That Exhibits Interstrain Variation
Sumner J, Childs J, Paddock C. Molecular Cloning and Characterization of the Ehrlichia chaffeensis Variable-Length PCR Target: an Antigen-Expressing Gene That Exhibits Interstrain Variation. Journal Of Clinical Microbiology 1999, 37: 1447-1453. PMID: 10203503, PMCID: PMC84798, DOI: 10.1128/jcm.37.5.1447-1453.1999.Peer-Reviewed Original ResearchConceptsOpen reading frameAmino acid sequenceApparent molecular massE. chaffeensisGenomic libraryMolecular cloningReading frameAcid sequenceDifferentiation of isolatesPCR targetsClose homologyMolecular massNucleotide sequencingImmunoreactive proteinDifferent isolatesDNA samplesInterstrain variationGenesRepeat unitsMolecular databasesCell culturesAmblyomma americanum ticksSequencePCR detectionChaffeensis
1995
Use of Bartonella Antigens for Serologic Diagnosis of Cat-scratch Disease at a National Referral Center
Dalton M, Robinson L, Cooper J, Regnery R, Olson J, Childs J. Use of Bartonella Antigens for Serologic Diagnosis of Cat-scratch Disease at a National Referral Center. JAMA Internal Medicine 1995, 155: 1670-1676. PMID: 7542443, DOI: 10.1001/archinte.1995.00430150164017.Peer-Reviewed Original ResearchConceptsCat-scratch diseaseIndirect fluorescent antibodySerum samplesB henselaeFluorescent antibodyNational referral centerStrict clinical definitionsUse of antigensReferral centerCat contactRegional adenopathyCat scratchClinical historyFourfold riseB quintanaBasis of causeClinical definitionClinical informationDiagnostic criteriaPatientsSerologic diagnosisDisease controlBartonella henselaeCat ageDisease
1993
Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York.
Schwartz B, Nadelman R, Fish D, Childs J, Forseter G, Wormser G. Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York. American Journal Of Tropical Medicine And Hygiene 1993, 48: 50-7. PMID: 8427388, DOI: 10.4269/ajtmh.1993.48.50.Peer-Reviewed Original ResearchConceptsSaliva antibodiesIndependent predictorsI. damminiLate-stage Lyme diseaseStrong independent predictorEnzyme-linked immunosorbentEngorgement indicesErythema migransProspective studyAntibody responseBiologic markersRisk factorsTick biteTick exposureNormal controlsSubject ageLogistic regressionLyme diseaseSalivary glandsOptical density valuesBiteTick engorgementConsistent changesDemographic correlatesAntibodies
1992
Comparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice
Hofmeister E, Markham R, Childs J, Arthur R. Comparison of polymerase chain reaction and culture for detection of Borrelia burgdorferi in naturally infected Peromyscus leucopus and experimentally infected C.B-17 scid/scid mice. Journal Of Clinical Microbiology 1992, 30: 2625-2631. PMID: 1400962, PMCID: PMC270489, DOI: 10.1128/jcm.30.10.2625-2631.1992.Peer-Reviewed Original Research