2005
Human Monocytotropic Ehrlichiosis
Dawson J, Ewing S, Davidson W, Childs J, Little S, Standaert S. Human Monocytotropic Ehrlichiosis. 2005, 239-257. DOI: 10.1128/9781555816490.ch14.Peer-Reviewed Original ResearchHuman monocytotropic ehrlichiosisMonocytotropic ehrlichiosisMild self-limiting symptomsSelf-limiting symptomsNonspecific febrile illnessSpectrum of manifestationsSeasonality of transmissionTick-borne zoonosisFebrile illnessAsymptomatic infectionClinical recognitionHigh riskRickettsial infectionEpidemiological studiesEtiologic agentFatal diseaseLaboratory diagnosisZoonotic diseaseEhrlichia chaffeensisLone star tickE. chaffeensisInfectionDiseaseEhrlichiosisUnited States
2001
Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in Persons Coinfected with Human Immunodeficiency Virus
Paddock C, Folk S, Shore G, Machado L, Huycke M, Slater L, Liddell A, Buller R, Storch G, Monson T, Rimland D, Sumner J, Singleton J, Bloch K, Tang Y, Standaert S, Childs J. Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in Persons Coinfected with Human Immunodeficiency Virus. Clinical Infectious Diseases 2001, 33: 1586-1594. PMID: 11568857, DOI: 10.1086/323981.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusImmunodeficiency virusE. ewingiiE. chaffeensisCases of ehrlichiosisDiagnosis of ehrlichiosisT-lymphocyte countsCells/microL.Ehrlichia ewingiiEhrlichia chaffeensisLife-threatening illnessLymphocyte countClinical courseHIV infectionMedical managementPatient cohortSevere manifestationsPatientsLaboratory evaluationEhrlichiosisChaffeensisInfectionEwingiiMultiple factorsVirus
1999
The Human Ehrlichioses in the United States - Volume 5, Number 5—October 1999 - Emerging Infectious Diseases journal - CDC
McQuiston J, Paddock C, Holman R, Childs J. The Human Ehrlichioses in the United States - Volume 5, Number 5—October 1999 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 1999, 5: 635-642. PMID: 10511519, PMCID: PMC2627718, DOI: 10.3201/eid0505.990504.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisHuman monocytic ehrlichiosisInfectious Diseases journal - CDCState health departmentsPublic health importanceSerologic testingNational surveillanceHealth departmentsHuman ehrlichiosesHealth importanceDisease controlGranulocytic ehrlichiosisMonocytic ehrlichiosisEhrlichiosisUpper midwestern statesAnnual numberBetter assessmentCasesPreventionDiagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum
Comer J, Nicholson W, Sumner J, Olson J, Childs J. Diagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum. Journal Of Clinical Microbiology 1999, 37: 31-34. PMID: 9854059, PMCID: PMC84159, DOI: 10.1128/jcm.37.1.31-34.1999.Peer-Reviewed Original ResearchConceptsDetermination of etiologyAcute-phase seraHuman granulocytic ehrlichiosisSerologic testingHuman ehrlichiosisAcute-phase serum samplesEarly detectionWhole blood specimensPCR assaysBlood specimensPCR testingEtiologic agentGranulocytic ehrlichiosisEtiologyHGE agentSimilar titersSerum samplesExposure historyTitersEhrlichia chaffeensisEhrlichiosisFourfold differenceE. chaffeensisSerumAntibodiesIdentity of Ehrlichial DNA Sequences Derived from Ixodes ricinus Ticks with Those Obtained from Patients with Human Granulocytic Ehrlichiosis in Slovenia
Petrovec M, Sumner J, Nicholson W, Childs J, Strle F, Barlič J, Lotrič-Furlan S, AvšičŽupanc T. Identity of Ehrlichial DNA Sequences Derived from Ixodes ricinus Ticks with Those Obtained from Patients with Human Granulocytic Ehrlichiosis in Slovenia. Journal Of Clinical Microbiology 1999, 37: 209-210. PMID: 9854093, PMCID: PMC84210, DOI: 10.1128/jcm.37.1.209-210.1999.Peer-Reviewed Original Research
1998
Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia
Lotrič-Furlan S, Petrovec M, Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia. Clinical Infectious Diseases 1998, 27: 424-428. PMID: 9770134, DOI: 10.1086/514683.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisHGE agentFebrile illnessLaboratory findingsTick biteAcute human granulocytic ehrlichiosisGranulocytic ehrlichiosisTick-borne diseaseAcute infectionAntibiotic therapyDisease coursePolymerase chain reaction analysisClinical featuresDetectable antibodiesDifferential diagnosisFirst visitChain reaction analysisPatientsHigh titersIllnessEhrlichial organismsEhrlichiosisAntibodiesBiteUnited States
1995
Ehrlichiosis in a Golf-Oriented Retirement Community
Standaert S, Dawson J, Schaffner W, Childs J, Biggie K, Singleton J, Gerhardt R, Knight M, Hutcheson R. Ehrlichiosis in a Golf-Oriented Retirement Community. New England Journal Of Medicine 1995, 333: 420-425. PMID: 7616991, DOI: 10.1056/nejm199508173330704.Peer-Reviewed Original ResearchConceptsE. chaffeensis infectionCase-control studySerologic testingCommunity AMedical history reviewLone star tickRisk of infectionCommunity BAnnual incidenceSerologic evidencePolymerase chain reactionTick biteRetirement communityInfectionEhrlichiosisEndemic diseaseChain reactionEhrlichia chaffeensisHigh rateSurvey participantsPercentTicksInsect repellentOutbreakRecreational activities
1994
Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis
Dawson J, Stallknecht D, Howerth E, Warner C, Biggie K, Davidson W, Lockhart J, Nettles V, Olson J, Childs J. Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Journal Of Clinical Microbiology 1994, 32: 2725-2728. PMID: 7852563, PMCID: PMC264150, DOI: 10.1128/jcm.32.11.2725-2728.1994.Peer-Reviewed Original ResearchConceptsHuman ehrlichiosisE. canisE. chaffeensisEtiologic agentAbsence of seroconversionEhrlichia chaffeensisMacrophage-type cellsE. chaffeensis infectionLymph nodesPeripheral bloodClinical diseaseDay 10InfectionEhrlichia canisEhrlichiosisAntibodiesWhite-tailed deerChaffeensisNegative controlCanisReservoir hostsCompetent reservoirsWeeksTick vectorSeroconversion