1999
Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid
Combes B, Carithers R, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Risser R, Rossi S, Hofmann A. Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid. Hepatology 1999, 29: 1649-1654. PMID: 10347103, PMCID: PMC4004074, DOI: 10.1002/hep.510290618.Peer-Reviewed Original ResearchMeSH KeywordsBileBile Acids and SaltsChenodeoxycholic AcidCholic AcidChromatography, GasChromatography, High Pressure LiquidDeoxycholic AcidDouble-Blind MethodDrug Administration ScheduleFemaleHumansLithocholic AcidLiver Cirrhosis, BiliaryMaleMiddle AgedPlacebosRegression AnalysisReproducibility of ResultsTime FactorsUrsodeoxycholic AcidConceptsPrimary biliary cirrhosisBile acid compositionUrsodeoxycholic acidBile acidsBiliary cirrhosisSeverity of PBCSingle bedtime dosePlacebo-controlled trialBiliary bile acidsEndogenous bile acidsMajor bile acidsBedtime dosePlacebo medicationDuodenal bileHigh-pressure liquid chromatography methodPatientsNormal personsBileSignificant decreaseCirrhosisAcid compositionCDCATaurineLiquid chromatography methodYears
1987
Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles.
Moseley R, Ballatori N, Smith D, Boyer J. Ursodeoxycholate stimulates Na+-H+ exchange in rat liver basolateral plasma membrane vesicles. Journal Of Clinical Investigation 1987, 80: 684-690. PMID: 3040805, PMCID: PMC442291, DOI: 10.1172/jci113122.Peer-Reviewed Original Research
1979
Phenobarbital treatment in primary biliary cirrhosis. Differences in bile acid composition between responders and nonresponders.
Stellaard F, Bolt M, Boyer J, Klein P. Phenobarbital treatment in primary biliary cirrhosis. Differences in bile acid composition between responders and nonresponders. Translational Research 1979, 94: 853-61. PMID: 501209.Peer-Reviewed Original Research
1978
Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate
Bagheri S, Bolt M, Boyer J, Palmer R. Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate. Gastroenterology 1978, 74: 188-192. PMID: 620891, DOI: 10.1016/0016-5085(78)90793-x.Peer-Reviewed Original ResearchConceptsCertain bile acidsBiliary tractBile acidsBiliary tract epitheliumSingle oral dosesBile duct hyperplasiaBile acid poolBile saltsDuctular cell hyperplasiaPeliosis hepatisOral dosesHepatocellular necrosisBile ductCell hyperplasiaDuct hyperplasiaEnterohepatic circulationHepatic nodulesProliferative activityThymidine incorporationLiverEarly effectsLithocholateMouse liverDosesCell kinetics