2016
A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization
Xu S, Soroka CJ, Sun AQ, Backos DS, Mennone A, Suchy FJ, Boyer JL. A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization. PLOS ONE 2016, 11: e0158269. PMID: 27351185, PMCID: PMC4924846, DOI: 10.1371/journal.pone.0158269.Peer-Reviewed Original ResearchConceptsMembrane localizationAlpha subunitBeta subunitDileucine motifPlasma membrane localizationDi-leucine motifExtracellular N-terminal regionCo-immunoprecipitation studiesBasolateral membrane localizationN-terminal regionSite-directed mutagenesisAA mutantProtein associationBeta mutantsN-terminusMultiple speciesPhysical associationMembrane biotinylationHEK293 cellsSubunitsAA mutationsMembrane expressionAlpha/betaMutantsMotif
2000
ATP-dependent GSH and glutathioneS-conjugate transport in skate liver: role of an Mrp functional homologue
Rebbeor J, Connolly G, Henson J, Boyer J, Ballatori N. ATP-dependent GSH and glutathioneS-conjugate transport in skate liver: role of an Mrp functional homologue. AJP Gastrointestinal And Liver Physiology 2000, 279: g417-g425. PMID: 10915652, DOI: 10.1152/ajpgi.2000.279.2.g417.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsAnion Transport ProteinsAnionsATP-Binding Cassette TransportersBileBiological TransportCarrier ProteinsCell MembraneEnzyme InhibitorsGlutathioneLiverMaleOxidation-ReductionProtein BindingRatsRats, Sprague-DawleySkates, FishSubstrate SpecificityTaurocholic AcidTritiumConceptsATP-dependent transportLiver membrane vesiclesATP-dependent GSH transportMembrane vesiclesTransport activityATP-independent mechanismGlutathione-conjugate transportFunctional homologueMammalian cellsDNP-SG uptakePlasma membraneHomologous proteinsSkate liverGSH transportLow-affinity pathwayLittle skateMRP familyMultidrug resistance-associated protein 1GSH effluxFunctional assaysProtein 1First direct evidenceProtein bandsDirect evidenceHomologues
1979
Chlorpromazine and Its Metabolites Alter Polymerization and Gelation of Actin
Elias E, Boyer J. Chlorpromazine and Its Metabolites Alter Polymerization and Gelation of Actin. Science 1979, 206: 1404-1406. PMID: 574316, DOI: 10.1126/science.574316.Peer-Reviewed Original Research