2017
Mechanisms of bile acid mediated inflammation in the liver
Li M, Cai SY, Boyer JL. Mechanisms of bile acid mediated inflammation in the liver. Molecular Aspects Of Medicine 2017, 56: 45-53. PMID: 28606651, PMCID: PMC5662014, DOI: 10.1016/j.mam.2017.06.001.Peer-Reviewed Original ResearchConceptsLiver injuryBile acidsCholestatic animal modelsCauses of cholestasisCholestatic liver injuryInnate immune cellsBiliary injuryNeutrophil recruitmentBile flowImmune cellsEffective therapyInflammatory responseAnimal modelsMolecular mediatorsCholestasisInjuryNovel targetLiverElevated levelsPathological processesMolecular mechanismsHepatocytesInflammationPatientsPathogenesisStudies on the mechanisms of bile acid initiated hepatic inflammation in cholestatic liver injury.
Cai SY, Boyer JL. Studies on the mechanisms of bile acid initiated hepatic inflammation in cholestatic liver injury. Inflammation And Cell Signaling 2017, 4 PMID: 28804737, PMCID: PMC5553904, DOI: 10.14800/ics.1561.Peer-Reviewed Original Research
2001
Cholestatic syndromes
Trauner M, Boyer J. Cholestatic syndromes. Current Opinion In Gastroenterology 2001, 17: 242-256. PMID: 17031165, DOI: 10.1097/00001574-200105000-00007.Peer-Reviewed Original ResearchCholestatic syndromeTotal parenteral nutrition-induced cholestasisParenteral nutrition-induced cholestasisHereditary cholestatic syndromesPrimary biliary cirrhosisCholestasis of pregnancyCholestatic liver diseaseDrug-induced cholestasisHepatobiliary transport proteinsBiliary cirrhosisClinical featuresLiver diseaseBile secretionCholestasisSyndromePathogenesisImportant new studiesNew studiesCholangitisCirrhosisPregnancyDiseaseSecretionTransporter gene
2000
Cholestatic syndromes
Trauner M, Boyer J. Cholestatic syndromes. Current Opinion In Gastroenterology 2000, 16: 239-250. PMID: 17023881, DOI: 10.1097/00001574-200005000-00006.Peer-Reviewed Original Research
1999
Cholestatic syndromes
Trauner M, Boyer J. Cholestatic syndromes. Current Opinion In Gastroenterology 1999, 15: 217-228. PMID: 17023948, DOI: 10.1097/00001574-199905000-00006.Peer-Reviewed Original ResearchCholestatic syndromeBile duct lossPathogenesis of pruritusCholestatic liver injuryPrimary biliary cirrhosisCholestasis of pregnancyCholestatic liver diseaseDrug-induced cholestasisNew treatment strategiesHepatobiliary transport systemsBiliary cirrhosisLiver injuryClinical featuresLiver diseaseTreatment strategiesDuct lossCholestasisSyndromePathogenesisImportant new studiesNew studiesImportant mechanismCholangitisCirrhosisPruritus
1987
Manganese-bilirubin cholestasis. Further studies in pathogenesis.
Witzleben C, Boyer J, Ng O. Manganese-bilirubin cholestasis. Further studies in pathogenesis. Laboratory Investigation 1987, 56: 151-4. PMID: 3807313.Peer-Reviewed Original Research
1970
Inhibition of Postheparin Lipolytic Activity in Uremia and its Relationship to Hypertriglyceridemia 1
Boyer J, Scheig R. Inhibition of Postheparin Lipolytic Activity in Uremia and its Relationship to Hypertriglyceridemia 1. Experimental Biology And Medicine 1970, 134: 603-605. PMID: 5431345, DOI: 10.3181/00379727-134-34842.Peer-Reviewed Original ResearchConceptsPostheparin lipolytic activityUremic patientsTriglyceride levelsPathogenesis of hypertriglyceridemiaTwice-weekly hemodialysisSerum triglyceride levelsLipoprotein electrophoretic patternsPlasma triglyceride levelsDegree of impairmentRenal failureChronic uremiaLipolytic activityPlasma clearanceNormal subjectsRat chylomicronsPatientsDegree of inhibitionPlasma inhibitorUremiaInhibitionHypertriglyceridemiaHemodialysisHyperlipemiaElectrophoretic patternsPathogenesis