2020
Hormonal Regulation of Cholangiocyte Secretion
Gigliozzi A, Fraioli F, Boyer J. Hormonal Regulation of Cholangiocyte Secretion. 2020, 89-95. DOI: 10.1201/9780367813888-8.Peer-Reviewed Original ResearchVasoactive intestinal peptideCholangiocyte secretionBicarbonate secretionBicarbonate-rich choleresisPost-prandial phaseExert inhibitory effectsCGMP-independent pathwayBicarbonate excretionIntestinal peptideParasympathetic systemPKA-dependent pathwayHepatic bileCholangiocyte proliferationActivation of calcineurinMaximal stimulationInhibitory effectSecretionBicarbonate requirementEnhanced expressionAdenylyl cyclaseHormonal regulationDigestive functionMajor determinantActivationCorticosteroids
1994
Characteristics of bile salt uptake into skate hepatocytes
Fricker G, Dubost V, Finsterwald K, Boyer J. Characteristics of bile salt uptake into skate hepatocytes. Biochemical Journal 1994, 299: 665-670. PMID: 8192655, PMCID: PMC1138072, DOI: 10.1042/bj2990665.Peer-Reviewed Original ResearchConceptsOrganic anion transport systemBile salt uptakeBile alcoholsBile saltsBeta-cholestane-3 alphaBile salt transportUnconjugated bile saltsTaurine-conjugated bile saltsHepatic uptakeAlpha-triolSkate bileInhibitory effectLiver cellsSkate hepatocytesIndependent transport systemsCholyltaurine transportCholyltaurineHepatocytesInhibitionAlphaUptakeSpecificity
1992
Papaverine inhibits transcytotic vesicle transport and lipid excretion into bile in isolated perfused rat liver
Hayakawa T, Katagiri K, Hoshino M, Nakai T, Ohiwa T, Kumai T, Miyaji M, Takeuchi T, Corasanti J, Boyer J. Papaverine inhibits transcytotic vesicle transport and lipid excretion into bile in isolated perfused rat liver. Hepatology 1992, 16: 1036-1042. PMID: 1398483, DOI: 10.1002/hep.1840160429.Peer-Reviewed Original ResearchConceptsSodium taurocholate infusionBiliary excretionTaurocholate infusionPhosphodiesterase inhibitorBile acidsNonspecific smooth muscle relaxantSmooth muscle relaxantRat liver modelRat liverLipid excretionContinuous infusionBile flowMuscle relaxantsPapaverine inhibitsConstant infusionHorseradish peroxidaseInfusionPapaverineExcretionInhibitory effectCyclic GMPBileLiverLiver modelCyclic AMP