Determinants of glutathione efflux and biliary GSH/GSSG ratio in perfused rat liver
Ballatori N, Truong A, K. A, Boyer J. Determinants of glutathione efflux and biliary GSH/GSSG ratio in perfused rat liver. American Journal Of Physiology 1989, 256: g482-g490. PMID: 2564253, DOI: 10.1152/ajpgi.1989.256.3.g482.Peer-Reviewed Original ResearchConceptsGamma-glutamyl transferase activityO2 deliveryBiliary glutathioneHepatic effluxSinusoidal effluxKrebs-Ringer bicarbonate bufferGlutathione effluxRat liverEfflux of glutathioneGSH/GSSG ratioRed blood cellsPerfusion flow rateFluorocarbon emulsionsBile flowTissue GSHOxygen deliveryTransferase activityAT-125LiverBovine red blood cellsPerfusate compositionBlood cellsBileGSSG levelsGSSG ratio