2006
The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver
Meier-Abt F, Hammann-Hänni A, Stieger B, Ballatori N, Boyer J. The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver. Toxicology And Applied Pharmacology 2006, 218: 274-279. PMID: 17198718, DOI: 10.1016/j.taap.2006.11.015.Peer-Reviewed Original ResearchConceptsSkate liverToxic liver injuryFunctional transport activityLiver-specific OATPsOrganic anion transporting polypeptidesLiver injuryOrganic anion transportersWater-injected oocytesXenobiotic toxinsHepatocellular uptakeBile saltsSkate hepatocytesOATP substratesHuman brainLiverPresent studyOatps/OATPsAnion transportersOATPDemethylphalloinHepatocytesTransport activityToxinCellular uptakeUptake
1998
Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets
Roelofsen H, Soroka C, Keppler D, Boyer J. Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets. Journal Of Cell Science 1998, 111: 1137-1145. PMID: 9512509, DOI: 10.1242/jcs.111.8.1137.Peer-Reviewed Original ResearchConceptsTransport proteinsApical membraneApical domainTransporter-containing vesiclesMultidrug resistance protein 2Protein 2Cell-cell contactMicrotubule-dependent fashionBasolateral plasma membraneApical proteinsEffect of cAMPVesicle trafficAnion transportersSecretory polarityOrganic anion transportersPlasma membraneCanalicular membraneAnion transport capacityTransport activityApical excretionApical poleCanalicular organic anion transportMultispecific organic anion transporterAmphiphilic organic anionsTransport function