Featured Publications
Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization
Lam CK, Yoo T, Hiner B, Liu Z, Grutzendler J. Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization. Nature 2010, 465: 478-482. PMID: 20505729, PMCID: PMC2879083, DOI: 10.1038/nature09001.Peer-Reviewed Original ResearchConceptsAge-related cognitive disordersBlood vesselsPossible therapeutic targetAged miceBlood flowTherapeutic targetCognitive disordersMice showBlood clotsEndothelial cellsUnderlying endotheliumMicroemboliExtravasationFibrinolysisVesselsRecanalizationEmboliPatientsStrokeEndotheliumMiceBloodBrainWeeksClots
2000
Multicolor “DiOlistic” Labeling of the Nervous System Using Lipophilic Dye Combinations
Gan W, Grutzendler J, Wong W, Wong R, Lichtman J. Multicolor “DiOlistic” Labeling of the Nervous System Using Lipophilic Dye Combinations. Neuron 2000, 27: 219-225. PMID: 10985343, DOI: 10.1016/s0896-6273(00)00031-3.Peer-Reviewed Original ResearchConceptsNervous systemGolgi-like labelingNormal synaptic responsesComplex neuronal networksDendritic remodelingSynaptic responsesNeuronal preparationsNeuronal connectivityNeuronal circuitsIndividual neuronsNeuronsDye-coated particlesGene gunNeuronal networksStructural plasticityLipophilic dyeCellsGliaDiOlisticsLabeling