Genetic ancestry-associated differences in genomic profiling and treatment patterns in pancreatic ductal adenocarcinoma (PDAC).
Gaddy J, Li G, Keller-Evans R, Bray D, MILLS J, Oberstein P, Kunz P, Sivakumar S. Genetic ancestry-associated differences in genomic profiling and treatment patterns in pancreatic ductal adenocarcinoma (PDAC). Journal Of Clinical Oncology 2024, 42: 4138-4138. DOI: 10.1200/jco.2024.42.16_suppl.4138.Peer-Reviewed Original ResearchPancreatic ductal adenocarcinomaClinico-genomic databaseGenetic ancestryAFRS patientsSocioeconomic statusPattern of gene alterationsPotential impact of genomicsSNP-based approachTreatment patternsGenomic profilingPopulation-level risk factorsImpact of genomicsCancer treatment courseClinical care patternsLow socioeconomic statusComprehensive genomic profilingOverall US populationNon-genomic factorsYounger median ageRate of surgeryImpact patient outcomesGenomic differencesAncestry distributionGenomic landscapeAncestry groups