2017
Bone marrow adipocytes
Horowitz MC, Berry R, Holtrup B, Sebo Z, Nelson T, Fretz JA, Lindskog D, Kaplan JL, Ables G, Rodeheffer MS, Rosen CJ. Bone marrow adipocytes. Adipocyte 2017, 6: 193-204. PMID: 28872979, PMCID: PMC5638373, DOI: 10.1080/21623945.2017.1367881.Peer-Reviewed Original ResearchConceptsBone marrow adipocytesBone marrowMarrow adipocytesDistinct adipose depotsAdipose tissue increasesWhole-body metabolismHuman bone marrowAdipose depotsAdipose tissueBeige adipocytesBody metabolismMarrowLittle functional significanceFunctional significanceAdipocytesCell populationsTissue increasesInduction signalRecent dataCellsAdipokines
2014
Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue
Gao H, Mejhert N, Fretz JA, Arner E, Lorente-Cebrián S, Ehrlund A, Dahlman-Wright K, Gong X, Strömblad S, Douagi I, Laurencikiene J, Dahlman I, Daub CO, Rydén M, Horowitz MC, Arner P. Early B Cell Factor 1 Regulates Adipocyte Morphology and Lipolysis in White Adipose Tissue. Cell Metabolism 2014, 19: 981-992. PMID: 24856929, PMCID: PMC4109056, DOI: 10.1016/j.cmet.2014.03.032.Peer-Reviewed Original ResearchAdipocytesAdipogenesisAdipose Tissue, WhiteAdiposityAnimalsCells, CulturedDiabetes MellitusDiet, High-FatFemaleGene ExpressionHumansHypertrophyInflammationInsulin ResistanceLipolysisMaleMiceMice, Inbred C57BLMice, KnockoutRNA InterferenceRNA, Small InterferingTrans-ActivatorsTumor Necrosis Factor-alpha
2011
Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Festa E, Fretz J, Berry R, Schmidt B, Rodeheffer M, Horowitz M, Horsley V. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling. Cell 2011, 146: 761-771. PMID: 21884937, PMCID: PMC3298746, DOI: 10.1016/j.cell.2011.07.019.Peer-Reviewed Original ResearchConceptsAdipocyte lineage cellsStem cell nicheStem cell activityLineage cellsCell nicheSkin stem cell nichesStem cell functionEpithelial stem cell nicheStem cell activationEpithelial stem cell functionSkin stem cellsTissue homeostasisNiche cellsFunctional analysisAdipogenic cellsSkin homeostasisMammalian skinTransplantation experimentsStem cellsPrecursor cellsHair cyclingCell functionAdipocyte cellsNicheFunctional tissue
2008
Ebf1-dependent control of the osteoblast and adipocyte lineages
Hesslein DG, Fretz JA, Xi Y, Nelson T, Zhou S, Lorenzo JA, Schatz DG, Horowitz MC. Ebf1-dependent control of the osteoblast and adipocyte lineages. Bone 2008, 44: 537-546. PMID: 19130908, PMCID: PMC2657874, DOI: 10.1016/j.bone.2008.11.021.Peer-Reviewed Original ResearchConceptsNumber of osteoclastsBone formation parametersBone formation rateAdipocyte lineageBone marrow cellsOlfactory sensory neuronsSerum osteocalcinOsteoid volumeSensory neuronsAdipocyte numberBone marrowOsteoclast developmentMutant miceMarrow cellsMiceSubcutaneous sitesBone formationAdipocyte developmentStriking increaseDecreased depositionTranscription factorsOsteoblastsB cell fate specificationEBF1Adiposity