2012
Cryo-EM structure of a transcribing cypovirus
Yang C, Ji G, Liu H, Zhang K, Liu G, Sun F, Zhu P, Cheng L. Cryo-EM structure of a transcribing cypovirus. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 6118-6123. PMID: 22492979, PMCID: PMC3341035, DOI: 10.1073/pnas.1200206109.Peer-Reviewed Original ResearchConceptsNascent mRNATurret proteinFamily ReoviridaeCapsid shellConformational changesCapsid proteinMRNA transcriptionCryo-EM structureMajor capsid proteinGood model systemGuanylyltransferase domainTranscription cycleViral capsid proteinsIcosahedral viral capsidsCypovirusGenomic RNACryoelectron microscopyGMP moietyRNA virusesProteinViral capsidTranscriptionMRNAReoviridaeModel system
2011
Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping
Cheng L, Sun J, Zhang K, Mou Z, Huang X, Ji G, Sun F, Zhang J, Zhu P. Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 1373-1378. PMID: 21220303, PMCID: PMC3029759, DOI: 10.1073/pnas.1014995108.Peer-Reviewed Original ResearchConceptsCytoplasmic polyhedrosis virusDeduced amino acid sequenceCryo-EM structureRNA segment 7Amino acid sequenceMechanisms of mRNANascent mRNAEnzymatic domainsAcid sequenceCryoelectron microscopyFamily ReoviridaeProtein VP5Capsid shellPolyhedrosis virusFull atomic modelsAtomic modelStructural organizationGuanylyltransferaseMRNASegment 7ProteinCypovirus