2023
High-Resolution Structural Analysis of Dyneins by Cryo-electron Microscopy
Chai P, Rao Q, Wang Y, Zhang K. High-Resolution Structural Analysis of Dyneins by Cryo-electron Microscopy. Methods In Molecular Biology 2023, 2623: 257-279. PMID: 36602691, PMCID: PMC10371436, DOI: 10.1007/978-1-0716-2958-1_16.ChaptersConceptsCryo-electron microscopyHigh-resolution structural informationLarge molecular machineHigh-resolution structuresCryo-EM approachResolution structural analysisProtein complexesStructural biologistsCellular cargoMolecular machinesDyneinDepth mechanistic understandingMolecular motorsMechanistic understandingCiliary motilityFlexible conformationIntricate architectureStructural informationMacromolecular structureForce generatorStructural analysisBiologistsSimilar structureCargoMicroscopy
2012
Mechanistic Insights into Regulated Cargo Binding by ACAP1 Protein*
Bai M, Pang X, Lou J, Zhou Q, Zhang K, Ma J, Li J, Sun F, Hsu VW. Mechanistic Insights into Regulated Cargo Binding by ACAP1 Protein*. Journal Of Biological Chemistry 2012, 287: 28675-28685. PMID: 22645133, PMCID: PMC3436524, DOI: 10.1074/jbc.m112.378810.Peer-Reviewed Original ResearchConceptsGTPase-activating proteinsCargo bindingIntegrin recyclingRegulated transportArf6 GTPase-activating ProteinsADP-ribosylation factor (ARF) familyVesicular transport pathwaysMechanistic insightsEndocytic recyclingCoat complexSmall GTPasesCytoplasmic domainCoat componentsFurther mechanistic insightsProtein cargoFactor familyACAP1Functional studiesIntegrin β1Critical sequencesPhosphorylationBindingTransport pathwaysProteinCargo