Evaluating the risk of QTc prolongation associated with hydroxychloroquine use with antidepressants in lupus patients with fibromyalgia
Renaldi J, Koumpouras F, Dong X. Evaluating the risk of QTc prolongation associated with hydroxychloroquine use with antidepressants in lupus patients with fibromyalgia. Lupus 2021, 30: 1844-1848. PMID: 34353174, DOI: 10.1177/09612033211034562.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusQTc prolongationHCQ useLupus patientsQTc intervalFibromyalgia syndromeDose of hydroxychloroquineLethal ventricular arrhythmiasMild QTc prolongationElectronic medical recordsHydroxychloroquine useLupus erythematosusVentricular arrhythmiasMedical recordsBazett's formulaCardiological conditionsOverall prolongationSudden deathHydroxychloroquineImmunomodulatory propertiesAntidepressantsPatientsDrug useConcurrent useECG monitoring