Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation
Lim HC, Surovtsev IV, Beltran BG, Huang F, Bewersdorf J, Jacobs-Wagner C. Evidence for a DNA-relay mechanism in ParABS-mediated chromosome segregation. ELife 2014, 3: e02758. PMID: 24859756, PMCID: PMC4067530, DOI: 10.7554/elife.02758.Peer-Reviewed Original ResearchConceptsChromosome segregationPartition complexParA-like proteinBacterial chromosome segregationDNA-binding activityParABS systemCytoplasmic cargoCaulobacter crescentusDNA regionsBiochemical approachesIntracellular transportTranslocation forceCellular parametersChromosomesTransient tethersCrescentusParABSMajor roleSegregationComplexesMechanismProteinTranslocationConservationBacteria